User profiles for Stephan Hjorth

Stephan Hjorth

Professor of Pharmacology
Verified email at gu.se
Cited by 13142

8-Hydroxy-2-(dipropylamino) tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

…, U Hacksell, JLG Nilsson, S Hjorth… - Journal of medicinal …, 1981 - ACS Publications
We are currently investigating thepharmacological properties of 2-aminotetralins and related
compounds using biochemical and behavioral methods recently pub-lished. 1, 2 It has …

[HTML][HTML] Identification and characterisation of a novel splice variant of the human CB1 receptor

E Ryberg, HK Vu, N Larsson, T Groblewski, S Hjorth… - FEBS letters, 2005 - Elsevier
Cannabinoid ligands are implicated in many physiological processes and to date two
receptors have been identified. However, a growing body of evidence exists that suggests the …

Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis

S Hjorth, T Sharp - Life sciences, 1991 - Elsevier
Recent electrophysiological studies, measurements of 5-HT synthesis and in vivo voltammetry
recordings of 5-HT metabolism have suggested that serotoninergic neurones in the …

Long-term incidence of microvascular disease after bariatric surgery or usual care in patients with obesity, stratified by baseline glycaemic status: a post-hoc analysis …

…, PA Svensson, I Larsson, S Hjorth… - The lancet Diabetes & …, 2017 - thelancet.com
Background Bariatric surgery is associated with remission of diabetes and prevention of
diabetic complications in patients with obesity and type 2 diabetes. Long-term effects of bariatric …

Serotonin 5‐HT1A Autoreceptor Blockade Potentiates the Ability of the 5‐HT Reuptake Inhibitor Citalopram to Increase Nerve Terminal Output of 5‐HT In Vivo: A …

S Hjorth - Journal of neurochemistry, 1993 - Wiley Online Library
The present study addressed the possibility that disinhibition of serotonin (5‐HT)
autoreceptor‐mediated negative feedback might potentiate the elevation of nerve terminal 5‐HT …

Is stimulation of both D1 and D2 receptors necessary for the expression of dopamine-mediated behaviors?

FJ White, LM Bednarz, SR Wachtel, S Hjorth… - Pharmacology …, 1988 - Elsevier
Recent electrophysiological findings have indicated that D1 dopamine (DA) receptor
stimulations by SKF 38393 enables the inhibitory effects of the D2 receptor agonist quinpirole on …

Reoperations after bariatric surgery in 26 years of follow-up of the Swedish Obese Subjects Study

S Hjorth, I Näslund, JC Andersson-Assarsson… - JAMA …, 2019 - jamanetwork.com
Importance Bariatric surgery is an established treatment for obesity, but knowledge on the
long-term incidence of revisional surgery is scarce. Objective To determine the incidence and …

The putative 5-HT1B receptor agonist CP-93,129 suppresses rat hippocampal 5-HT release in vivo: comparison with RU 24969

S Hjorth, R Tao - European journal of pharmacology, 1991 - Elsevier
We have compared the ability of the new putatively specific 5-HT 1B receptor agonist CP-93,129
(3-(1,2,5,6-tetrahydropyrid-4-yl) pyrrolo[3,2-b]pyrid-5-one) and the structurally related …

Systemic PCP treatment elevates brain extracellular 5-HT: a microdialysis study in awake rats

P Martin, ML Carlsson, S Hjorth - Neuroreport, 1998 - journals.lww.com
THE NMDA receptor antagonist phencyclidine (PCP) has low micromolar affinity for the 5-HT
reuptake site, but it is uncertain whether PCP blocks 5-HT reuptake when given …

Application of brain microdialysis to study the pharmacology of the 5-HT1A autoreceptor

T Sharp, S Hjorth - Journal of neuroscience methods, 1990 - Elsevier
5-Hydroxytryptamine (5-HT) receptors of the 5-HT 1A subtype are localized on serotoninergic
cells and dendrites in the raphe nuclei of the brain stem and are believed to regulate …