The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial
publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 …

Adhesion-type heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptors (Adhesion-GPCRs) comprise a class of widely distributed seven-transmembrane …

Channelrhodopsin-2 (ChR2) has provided a breakthrough for the optogenetic control of
neuronal activity. In adult Drosophila melanogaster, however, its applications are severely …

10.7554/eLife.28360.001 Adhesion-type G protein-coupled receptors (aGPCRs), a large
molecule family with over 30 members in humans, operate in organ development, brain …

A rise in [Ca 2+ ] i provides the trigger for neurotransmitter release at neuronal boutons. We
have used confocal microscopy and Ca 2+ sensitive dyes to directly measure the action …

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial
publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key …

The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …

G-protein-coupled receptors (GPCRs) are typically regarded as chemosensors that control
cellular states in response to soluble extracellular cues. However, the modality of stimuli …

Adhesion class G protein-coupled receptors (aGPCR) form the second largest group of
seven-transmembrane-spanning (7TM) receptors whose molecular layout and function differ …

Adhesion G-protein-coupled receptors (aGPCRs) bear notable similarity to Notch proteins 1
, a class of surface receptors poised for mechano-proteolytic activation 2 , 3 – 4 , including …