Our understanding of the mechanisms mediating or moderating the placebo response to
medicines has grown substantially over the past decade and offers the opportunity to capitalize …

The placebo effect has often been considered a nuisance in basic and particularly clinical
research. This view has gradually changed in recent years due to deeper insight into the neuro…

Background: Placebo and nocebo effects occur in clinical or laboratory medical contexts
after administration of an inert treatment or as part of active treatments and are due to …

Evidence from behavioral and self-reported data suggests that the patients’ beliefs and
expectations can shape both therapeutic and adverse effects of any given drug. We investigated …

Placebos and placebo effects have held an ambivalent place in health care for at least 2
centuries. On the one hand, placebos are traditionally used as controls in clinical trials to correct …

Pain is a highly complex and subjective experience that is not linearly related to the nociceptive
input. What is clear from anecdotal reports over the centuries and more recently from …

Placebo analgesia is one of the most striking examples of the cognitive modulation of pain
perception and the underlying mechanisms are finally beginning to be understood. According …

Das große Standardwerk zur klinischen Neurologie liegt jetzt unter der Federführung des
international renommierten Herausgeberteams und der Mitarbeit von über 150 …

Placebo analgesia involves the endogenous opioid system, as administration of the opioid
antagonist naloxone decreases placebo analgesia. To investigate the opioidergic …

Placebo analgesia is a prime example of the impact that psychological factors have on pain
perception. We used functional magnetic resonance imaging of the human spinal cord to …