Most evidence indicates that, as for family CG protein–coupled receptors (GPCRs), family A
GPCRs form homo- and heteromers. Homodimers seem to be a predominant species, with …

During the last 10 years, adenosine deaminase (ADA), an enzyme considered to be
cytosolic, has been found on the cell surface of many cells, therefore it can be considered an …

Evidence has been obtained for adenosine/dopamine interactions in the central nervous
system. There exists an anatomical basis for the existence of functional interactions between …

The functional role of heteromers of G-protein-coupled receptors is a matter of debate. In the
present study, we demonstrate that heteromerization of adenosine A 1 receptors (A 1 Rs) …

Antagonistic and reciprocal interactions are known to exist between adenosine and dopamine
receptors in the striatum. In the present study, double immunofluorescence experiments …

The possible molecular basis for the previously described antagonistic interactions between
adenosine A 1 receptors (A 1 R) and dopamine D 1 receptors (D 1 R) in the brain have …

OBJECTIVE: Malnutrition is frequent in cancer. The objective of this study was to determine
the prevalence, in Spain, of malnutrition in cancer patients with advanced disease and to …

The physiological meaning of the coexpression of adenosine A2A receptors and group I
metabotropic glutamate receptors in γ- aminobutyric acid (GABA)ergic striatal neurons is …

Identification of higher-order oligomers in the plasma membrane is essential to decode the
properties of molecular networks controlling intercellular communication. We combined …

Exploring the role of cannabinoid CB 2 receptors in the brain, we present evidence of CB 2
receptor molecular and functional interaction with cannabinoid CB 1 receptors. Using …