[HTML][HTML] O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas
CH Fan, WL Liu, H Cao, C Wen, L Chen, G Jiang - Cell death & disease, 2013 - nature.com
Temozolomide (TMZ) is an alkylating agent currently used as first-line therapy for gliomas
treatment due to its DNA-damaging effect. However, drug resistance occurs, preventing multi-…
treatment due to its DNA-damaging effect. However, drug resistance occurs, preventing multi-…
Recent advances of cell membrane‐coated nanomaterials for biomedical applications
WL Liu, MZ Zou, SY Qin, YJ Cheng… - Advanced Functional …, 2020 - Wiley Online Library
… Liu's group used mannose modified tumor cell membrane to encapsulate R837-loaded
polymeric nanoparticles for effective antitumor vaccination. [ 143 ] Nanomaterials have also been …
polymeric nanoparticles for effective antitumor vaccination. [ 143 ] Nanomaterials have also been …
Advances in nanomaterials for treatment of hypoxic tumor
MZ Zou, WL Liu, HS Chen, XF Bai, F Gao… - National Science …, 2021 - academic.oup.com
… Liu's group designed a nanozyme based on Pt with dual enzyme-like activities (PtFe@Fe 3
O 4 … Liu's group developed a strategy to separately deliver H 2 O 2 and CAT to tumor sites by …
O 4 … Liu's group developed a strategy to separately deliver H 2 O 2 and CAT to tumor sites by …
[HTML][HTML] Hypoxia induces cyclooxygenase-2 via the NF-κB p65 transcription factor in human vascular endothelial cells
JF Schmedtje, YS Ji, WL Liu, RN DuBois… - Journal of Biological …, 1997 - ASBMB
The inducible cyclooxygenase, COX-2, has been associated with vascular inflammation
and cellular proliferation. We have discovered that hypoxia increases expression of the COX-2 …
and cellular proliferation. We have discovered that hypoxia increases expression of the COX-2 …
Cancer cell membrane camouflaged cascade bioreactor for cancer targeted starvation and photodynamic therapy
Selectively cuting off the nutrient supply and the metabolism pathways of cancer cells would
be a promising approach to improve the efficiency of cancer treatment. Here, a cancer …
be a promising approach to improve the efficiency of cancer treatment. Here, a cancer …
[HTML][HTML] The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial …
…, QL Kong, LH Xu, X Zhang, WL Liu… - The Journal of …, 2009 - Am Soc Clin Investig
The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is
dysregulated in various cancers, and its upregulation strongly correlates with an invasive …
dysregulated in various cancers, and its upregulation strongly correlates with an invasive …
Predictors and prognosis of inability to get up after falls among elderly persons
ME Tinetti, WL Liu, EB Claus - Jama, 1993 - jamanetwork.com
… From the Departments of Medicine (Dr Tinetti) and Epidemiology and Public Health (Mr Liu
and Dr … Tinetti ME, Liu W, Claus EB. Predictors and Prognosis of Inability to Get Up After Falls …
and Dr … Tinetti ME, Liu W, Claus EB. Predictors and Prognosis of Inability to Get Up After Falls …
Bmi-1 is a novel molecular marker of nasopharyngeal carcinoma progression and immortalizes primary human nasopharyngeal epithelial cells
LB Song, MS Zeng, WT Liao, L Zhang, HY Mo, WL Liu… - Cancer research, 2006 - AACR
The Bmi-1 oncoprotein regulates proliferation and oncogenesis in human cells. Its
overexpression leads to senescence bypass in human fibroblasts and immortalization of human …
overexpression leads to senescence bypass in human fibroblasts and immortalization of human …
[PDF][PDF] Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
A Böttger, V Böttger, A Sparks, WL Liu, SF Howard… - Current Biology, 1997 - cell.com
Background: The transcriptional activation function of the p53 tumour suppressor protein is
induced by DNA damage and results in growth arrest and/or apoptotic responses. A key …
induced by DNA damage and results in growth arrest and/or apoptotic responses. A key …
Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus-related coronavirus model
HH Fan, LQ Wang, WL Liu, XP An, ZD Liu… - Chinese medical …, 2020 - mednexus.org
… How to cite this article: Fan HH, Wang LQ, Liu WL, An XP, Liu ZD, He XQ, Song LH, Tong
YG. Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a …
YG. Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a …