Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in Vivo using an inhibitor of the aromatic amino acid decarboxylase

A Carlsson, JN Davis, W Kehr, M Lindqvist… - … archives of pharmacology, 1972 - Springer
DOPA and 5-HTP accumulated in vivo in rat brain after decarboxylase inhibition with NSD
1015 (3-hydroxybenzylhydrazine). This accumulation was linear for the first 30 min and …

Diffusion in regular and disordered lattices

JW Haus, KW Kehr - Physics Reports, 1987 - Elsevier
Classical diffusion of single particles on lattices with frozen-in disorder is surveyed. The
methods of continuous-time random walk theory are pedagogically developed and applications …

Modulation of anxiety by β-carbolines and other benzodiazepine receptor ligands: relationship of pharmacological to biochemical measures of efficacy

DN Stephens, HH Schneider, W Kehr, LH Jensen… - Brain research …, 1987 - Elsevier
Several β-carbolines and other benzodiazepines (BZ) receptor ligands have been investigated
for anxiolytic or anxiogenic action in 4 unrelated animal models of anxiety using rats. The …

Agonist-antagonist interaction on dopamine receptors in brain, as reflected in the rates of tyrosine and tryptophan hydroxylation

A Carlsson, W Kehr, M Lindqvist - Journal of Neural Transmission, 1977 - Springer
The effect of haloperidol and apomorphine, and both drugs in combination, on the first steps
in the synthesis of catecholamines and 5-hydroxytryptamine (5-HT) has been studied in …

Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.

DN Stephens, HH Schneider, W Kehr… - … of Pharmacology and …, 1990 - ASPET
Abecarnil (isopropyl 6-benzyloxy-4-methoxymethyl-beta-carboline-3-carboxylate) is a novel
ligand for central benzodiazepine (BZ) receptors, possessing anxiolytic and anticonvulsant …

Effect of lisuride and other ergot derivatives on monoaminergic mechanisms in rat brain

W Kehr - European Journal of Pharmacology, 1977 - Elsevier
Kehr, W., 1974a, A method for the isolation and determination of 3-methoxytyramine in brain
Kehr, W., 1974b, Temporal changes in catecholamine synthesis of rat forebrain structures …

A method for the determination of 3, 4-dihydroxyphenylalanine (DOPA) in brain

W Kehr, A Carlsson, M Lindqvist - Naunyn-Schmiedeberg's Archives of …, 1972 - Springer
The method is an extension of the chromatographic separation procedure for 5-HIAA and 5-HTP
published by Lindqvist (1971). Brain tissue is extracted with perchloric acid. After …

Water‐Soluble Phytotoxic Substances in Alfalfa Forage: Variation with Variety, Cutting, Year, and Stage of Growth1

WD Guenzi, WR Kehr, TM McCalla - Agronomy Journal, 1964 - Wiley Online Library
… WD Guenzi, WR Kehr, and TM McCalla2 … Effect on the growth of roots of corn seeds of a
w~ter extract of forage averaged over 2 alfalfa varieties* at 3 cuttings and at 6 stages of growth …

Distribution of dopamine in the rat cerebral cortex

W Kehr, M Lindqvist, A Carlsson - Journal of neural transmission, 1976 - Springer
The rat cerebral neocortex was sectioned by 3 transverse cuts and analyzed for dopamine
and noradrenaline. Dopamine concentration decreased gradually from the rostral (97±4 ng/g) …

Evaluation of the β-carboline ZK 93 426 as a benzodiazepine receptor antagonist

…, EN Petersen, C Braestrup, T Honoré, W Kehr… - …, 1984 - Springer
We describe here biochemical and pharmacological effects of the β-carboline ZK 93426, a
new and potent benzodiazepine (BZ) receptor antagonist. ZK 93426 was compared with Ro …