Histamine is a developmentally highly conserved autacoid found in most vertebrate tissues.
Its physiological functions are mediated by four 7-transmembrane G protein–coupled …

We wished to identify a CNS-sparing histamine H3 receptor antagonist for the treatment of
allergic rhinitis. We aimed for compounds with low permeability, high solubility, that were …

… In a study by Liu et al. [82], patients received liver grafts that were 52 ± 2% of the estimated
standard liver weight. At a median follow-up of 23 months, both patient and graft survival rates …

… Liu was an employee of Ziarco Pharma and was a stockholder of the Ziarco Group at the
time of the study, was cited on a patent that was held by Ziarco Pharma at the time of the study, …

Breast cancer remains a leading cause of cancer death in women, representing a significant
unmet medical need. Here, we disclose our discovery efforts culminating in a clinical …

This paper investigates a high-efficiency clamped-voltage dc-dc converter with reduced
reverse-recovery current and switch-voltage stress. In the circuit topology, it is designed by way …

… The study population consisted of 46 adult inpatients at either the Fu Wai or Ren Ming
hospitals. Patients were under cardiovascular evaluation, with most awaiting electrophysiological …

… , 23 Internal consistencies of the Chinese LS scores were 0.85 for a … LS was supported by
a positive correlation with another scale of social loneliness. The Chinese translation of the LS …

… From NBS analyses, group did not moderate the relationship between scores in LS and
any structural connections. Across all subjects, scores in LS were identified to be negatively …

Previous studies in our laboratory have shown that platelets are essential for the migration
of eosinophils into the lungs of allergic mice, and that this is dependent on the functional …