Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats

…, J Jittiwat, J Manikandan, CN Ong, EY Liya, WY Ong - Biomaterials, 2010 - Elsevier
Biodistribution of gold nanoparticles (AuNPs) in more than 25 organs were examined on 1
day, 1 week, 1 month and 2 months after a single intravenous (iv) injection in rats. Au was …

[HTML][HTML] Role of the prefrontal cortex in pain processing

WY Ong, CS Stohler, DR Herr - Molecular neurobiology, 2019 - Springer
The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral neocortex, …

Inhibitors of brain phospholipase A2 activity: their neuropharmacological effects and therapeutic importance for the treatment of neurologic disorders

AA Farooqui, WY Ong, LA Horrocks - Pharmacological reviews, 2006 - ASPET
The phospholipase A 2 family includes secretory phospholipase A 2 , cytosolic
phospholipase A 2 , plasmalogen-selective phospholipase A 2 , and calcium-independent …

Characterization, purification, and stability of gold nanoparticles

…, L Yang, LYL Yung, CN Ong, WY Ong… - Biomaterials, 2010 - Elsevier
Impurities in the synthesized gold nanoparticle (AuNP) solution are systematically identified
followed by determining an optimal purification process and evaluating the stability as well …

[HTML][HTML] Protective effects of ginseng on neurological disorders

WY Ong, T Farooqui, HL Koh, AA Farooqui… - Frontiers in aging …, 2015 - frontiersin.org
Ginseng (Order: Apiales, Family: Araliaceae, Genus: Panax) has been used as a traditional
herbal medicine for over 2000 years, and is recorded to have antianxiety, antidepressant …

Biochemical Aspects of Neurodegeneration in Human Brain: Involvement of Neural Membrane Phospholipids and Phospholipases A2

AA Farooqui, WY Ong, LA Horrocks - Neurochemical research, 2004 - Springer
Neural membrane phospholipids are hydrolyzed by a group of enzymes known as
phospholipases. This process results in the generation of second messengers such as arachidonic …

Genetic association studies of glutamate, GABA and related genes in schizophrenia and bipolar disorder: a decade of advance

SYT Cherlyn, P San Woon, JJ Liu, WY Ong… - Neuroscience & …, 2010 - Elsevier
Schizophrenia (SZ) and bipolar disorder (BD) are debilitating neurobehavioural disorders
likely influenced by genetic and non-genetic factors and which can be seen as complex …

[HTML][HTML] Bioinspired cell-derived nanovesicles versus exosomes as drug delivery systems: a cost-effective alternative

WJ Goh, S Zou, WY Ong, F Torta, AF Alexandra… - Scientific reports, 2017 - nature.com
Cell Derived Nanovesicles (CDNs) have been developed from the rapidly expanding field
of exosomes, representing a class of bioinspired Drug Delivery Systems (DDS). However, …

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 1 …

…, EE Michalak, J Sareen, WY Song… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT) conducted
a revision of the 2009 guidelines by updating the evidence and recommendations. The …

Autophagy plays a protective role during zVAD-induced necrotic cell death

…, Q Huang, YS Kim, N Pan, WY Ong, Z Liu, CN Ong… - Autophagy, 2008 - Taylor & Francis
The aim of this study is to examine the role of autophagy in cell death by using a well-established
system in which zVAD, a pan-caspase inhibitor, induces necrotic cell death in L929 …