G protein-coupled receptor-dependent development of human frontal cortex
X Piao, RS Hill, A Bodell, BS Chang… - Science, 2004 - science.org
The mammalian cerebral cortex is characterized by complex patterns of anatomical and
functional areas that differ markedly between species, but the molecular basis for this functional …
functional areas that differ markedly between species, but the molecular basis for this functional …
[PDF][PDF] Single-cell RNA sequencing of microglia throughout the mouse lifespan and in the injured brain reveals complex cell-state changes
Microglia, the resident immune cells of the brain, rapidly change states in response to their
environment, but we lack molecular and functional signatures of different microglial …
environment, but we lack molecular and functional signatures of different microglial …
A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding
…, AK Muthukumar, B Stevens, H Umemori, X Piao - The EMBO …, 2020 - embopress.org
Developmental synaptic remodeling is important for the formation of precise neural circuitry,
and its disruption has been linked to neurodevelopmental disorders such as autism and …
and its disruption has been linked to neurodevelopmental disorders such as autism and …
G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination
…, Z Jin, N Strokes, S Li, X Piao - Proceedings of the …, 2011 - National Acad Sciences
GPR56, an orphan G protein-coupled receptor (GPCR) from the family of adhesion GPCRs,
plays an indispensable role in cortical development and lamination. Mutations in the GPR56 …
plays an indispensable role in cortical development and lamination. Mutations in the GPR56 …
Role of macrophages in Wallerian degeneration and axonal regeneration after peripheral nerve injury
The peripheral nervous system (PNS) has remarkable regenerative abilities after injury.
Successful PNS regeneration relies on both injured axons and non-neuronal cells, including …
Successful PNS regeneration relies on both injured axons and non-neuronal cells, including …
International union of basic and clinical pharmacology. xciv. adhesion g protein–coupled receptors
…, DC Martinelli, KR Monk, MC Peeters, X Piao… - Pharmacological …, 2015 - ASPET
The Adhesion family forms a large branch of the pharmacologically important superfamily of
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …
G protein–coupled receptors (GPCRs). As Adhesion GPCRs increasingly receive attention …
[PDF][PDF] Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids
…, M Haeussler, KB Hengen, RR Ransohoff, X Piao… - Cell Stem Cell, 2021 - cell.com
Microglia are resident macrophages in the brain that emerge in early development and respond
to the local environment by altering their molecular and phenotypic states. Fundamental …
to the local environment by altering their molecular and phenotypic states. Fundamental …
[PDF][PDF] The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211
…, M Ghidinelli, ML Feltri, T Schöneberg, X Piao… - Neuron, 2015 - cell.com
Myelin ensheathes axons to allow rapid propagation of action potentials and proper nervous
system function. In the peripheral nervous system, Schwann cells (SCs) radially sort axons …
system function. In the peripheral nervous system, Schwann cells (SCs) radially sort axons …
GPR56 regulates pial basement membrane integrity and cortical lamination
GPR56 is a member of the family of adhesion G-protein-coupled receptors that have a large
extracellular region containing a GPS (G-protein proteolytic site) domain. Loss-of-function …
extracellular region containing a GPS (G-protein proteolytic site) domain. Loss-of-function …
[HTML][HTML] The association of COVID-19 infection in pregnancy with preterm birth: A retrospective cohort study in California
…, SP Oltman, MS Pantell, X Piao… - The Lancet Regional …, 2021 - thelancet.com
Introduction: Our understanding of the association between coronavirus disease 19 (COVID-19)
and preterm or early term birth among racially and ethnically diverse populations and …
and preterm or early term birth among racially and ethnically diverse populations and …