Therapeutic targets: progress of their exploration and investigation of their characteristics
Modern drug discovery is primarily based on the search and subsequent testing of drug
candidates acting on a preselected therapeutic target. Progress in genomics, protein structure, …
candidates acting on a preselected therapeutic target. Progress in genomics, protein structure, …
TTD: therapeutic target database
A number of proteins and nucleic acids have been explored as therapeutic targets. These
targets are subjects of interest in different areas of biomedical and pharmaceutical research …
targets are subjects of interest in different areas of biomedical and pharmaceutical research …
SVM-Prot: web-based support vector machine software for functional classification of a protein from its primary sequence
Prediction of protein function is of significance in studying biological processes. One approach
for function prediction is to classify a protein into functional family. Support vector machine …
for function prediction is to classify a protein into functional family. Support vector machine …
Acoustic attenuation performance of circular expansion chambers with extended inlet/outlet
A Selamet, ZL Ji - Journal of Sound and Vibration, 1999 - Elsevier
The acoustic attenuation performance of circular expansion chambers with extended inlet/outlet
is investigated. Three approaches are employed to determine the transmission loss: (1) …
is investigated. Three approaches are employed to determine the transmission loss: (1) …
Enzyme family classification by support vector machines
One approach for facilitating protein function prediction is to classify proteins into functional
families. Recent studies on the classification of G‐protein coupled receptors and other …
families. Recent studies on the classification of G‐protein coupled receptors and other …
Briefing in family characteristics of microRNAs and their applications in cancer research
MicroRNAs (miRNAs) are endogenous, short, non-coding RNA molecules that are directly
involved in the post-transcriptional regulation of gene expression. Dysregulation of miRNAs is …
involved in the post-transcriptional regulation of gene expression. Dysregulation of miRNAs is …
Drug Adverse Reaction Target Database (DART) Proteins Related to Adverse Drug Reactions
An adverse drug reaction (ADR) often results from interaction of a drug or its metabolites
with specific protein targets important in normal cellular function. Knowledge about these …
with specific protein targets important in normal cellular function. Knowledge about these …
TiSGeD: a database for tissue-specific genes
SJ Xiao, C Zhang, Q Zou, ZL Ji - Bioinformatics, 2010 - academic.oup.com
The tissue-specific genes are a group of genes whose function and expression are preferred
in one or several tissues/cell types. Identification of these genes helps better understanding …
in one or several tissues/cell types. Identification of these genes helps better understanding …
An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development
…, S Tian, H Gao, W Miao, Y Liu, H Wang, C Yin, ZL Ji… - Cell, 2023 - cell.com
Macrophages are heterogeneous and play critical roles in development and disease, but
their diversity, function, and specification remain inadequately understood during human …
their diversity, function, and specification remain inadequately understood during human …
[HTML][HTML] PaGenBase: a pattern gene database for the global and dynamic understanding of gene function
Pattern genes are a group of genes that have a modularized expression behavior under
serial physiological conditions. The identification of pattern genes will provide a path toward a …
serial physiological conditions. The identification of pattern genes will provide a path toward a …