GABA, bicuculline and central inhibition.

DR Curtis, AW Duggan, D Felix, GAR Johnston - Nature, 1970 - search.ebscohost.com
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Bicuculline, an antagonist of GABA and synaptic inhibition in the spinal cord of the cat

DR Curtis, AW Duggan, D Felix, GAR Johnston - Brain research, 1971 - Elsevier
(1) A study has been made of the effects of bicuculline, a phthalide isoquinoline convulsant
alkaloid, on the inhibition of spinal neurones by amino acids and the synaptic inhibition of …

Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat

AW Duggan, IA Hendry, CR Morton, WD Hutchinson… - Brain research, 1988 - Elsevier
In barbiturate-anaesthetized spinal cats, antibody microprobes were used to examine
immunoreactive substance P (irSP) release at sites within the spinal cord following cutaneous …

Mechanical allodynia following contusion injury of the rat spinal cord is associated with loss of GABAergic inhibition in the dorsal horn

GM Drew, PJ Siddall, AW Duggan - Pain, 2004 - journals.lww.com
The present study investigated whether mechanical allodynia following contusive spinal cord
injury (SCI) of the thoracic segments 12 and 13 of the rat was associated with a reduction …

The specificity of strychnine as a glycine antagonist in the mammalian spinal cord

DR Curtis, AW Duggan, GAR Johnston - Experimental Brain Research, 1971 - Springer
An investigation was made of the influence of strychnine on the depression of the firing of
spinal interneurones and Renshaw cells by glycine, GABA, nor-adrenaline and 3-…

Thalamic neuronal activity in rats with mechanical allodynia following contusive spinal cord injury

MB Gerke, AW Duggan, L Xu, PJ Siddall - Neuroscience, 2003 - Elsevier
Pain and allodynia following spinal cord injury are poorly understood and difficult to treat.
Since there is evidence that supraspinal mechanisms are important in such pain, we have …

Antagonism between bicuculline and GABA in the cat brain

DR Curtis, AW Duggan, D Felix, GAR Johnston… - Brain Research, 1971 - Elsevier
(1) An investigation was made of the effects of bicuculline on the inhibition by amino acids
of neurones in the lateral vestibular nucleus, the ventrobasal thalamus, and the cerebellar, …

Noxious heating of the skin releases immunoreactive substance P in the substantia gelatinosa of the cat: a study with antibody microprobes

AW Duggan, CR Morton, ZQ Zhao, IA Hendry - Brain research, 1987 - Elsevier
Using a new method, the antibody microprobe technique, the release of immunoreactive
substance P (SPiR) in the dorsal horn in response to noxious heating of the skin, was studied in …

Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: a study with antibody microprobes

HG Schaible, B Jarrott, PJ Hope, AW Duggan - Brain research, 1990 - Elsevier
In anaesthetized spinal cats, the release of immunoreactive substance P in the spinal cord
during development of an acute inflammation in one knee joint was studied with antibody …

Bicuculline and spinal inhibition produced by dorsal column stimulation in the cat

AW Duggan, FW Foong - Pain, 1985 - journals.lww.com
: In barbiturate anaesthetized cats, dorsal column stimulation inhibited ascending volleys
recorded in the antero-lateral spinal fasciculus from electrical stimulation of the contralateral …