User profiles for C. Coddou

Claudio Coddou

Universidad Católica del Norte
Verified email at ucn.cl
Cited by 1742

Activation and regulation of purinergic P2X receptor channels

C Coddou, Z Yan, T Obsil, JP Huidobro-Toro… - Pharmacological …, 2011 - ASPET
… Each subunit contains a large ectodomain, two transmembrane domains, and intracellular N
and C … The N- and C- domains provide the structures that determine the kinetics of receptor …

Allosteric modulation of ATP-gated P2X receptor channels

C Coddou, SS Stojilkovic, JP Huidobro-Toro - 2011 - degruyter.com
C-termini ranges from around 30 amino acids (P2X6R) to approximately 215 residues (P2X7R).
Both N- and C-… The C-terminal tail of P2X2R plays important roles in determining the rate …

[HTML][HTML] Roles of the unsaturated fatty acid docosahexaenoic acid in the central nervous system: Molecular and cellular insights

…, M Reyna-Jeldes, L Ortega, C Coddou… - International Journal of …, 2022 - mdpi.com
Fatty acids (FAs) are essential components of the central nervous system (CNS), where they
exert multiple roles in health and disease. Among the FAs, docosahexaenoic acid (DHA) …

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor

C Acuña‐Castillo, C Coddou, P Bull… - Journal of …, 2007 - Wiley Online Library
… Oocytes were next incubated at 15C for about 48 h in Barth’s solution [NaCl, 88; KCl, 1;
NaHCO 3 , 2.4; HEPES, 10; Ca(NO 3 ) 2 , 0.33; CaCl 2 , 0.91; MgSO 4 , 0.82 mmol/L; pH 7.4] …

Prenatal to early postnatal nicotine exposure impairs central chemoreception and modifies breathing pattern in mouse neonates: a probable link to sudden infant …

J Eugenín, M Otárola, E Bravo, C Coddou… - Journal of …, 2008 - Soc Neuroscience
… Dams were maintained in separate cages with water and food ad libitum at 22C under a
12 h light/dark cycle. After finishing the experimental protocols, animals were killed with an …

Characterization of the antagonist actions of 5-BDBD at the rat P2X4 receptor

C Coddou, R Sandoval, MJ Hevia, SS Stojilkovic - Neuroscience letters, 2019 - Elsevier
… Slices were transferred to an interface storage chamber containing artificial cerebrospinal
fluid (aCSF) saturated with 95% O2 / 5% CO2 and were left at least 1 h at 37 C. After this …

Autocrine and paracrine purinergic signaling in the most lethal types of cancer

…, M Díaz-Muñoz, JA Madariaga, C Coddou… - Purinergic …, 2021 - Springer
Cancer comprises a collection of diseases that occur in almost any tissue and it is
characterized by an abnormal and uncontrolled cell growth that results in tumor formation and …

Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH

K Kaszas, JM Keller, C Coddou, SK Mishra… - … of Pharmacology and …, 2012 - ASPET
… as a multimodal nociceptor gated by temperatures greater than 43C, protons, and small-molecule
vanilloid … Under inflammatory-mimetic conditions of low pH (6.0) and protein kinase C

[HTML][HTML] Understanding the role of ATP release through connexins hemichannels during neurulation

…, C Coddou, L Bascunan-Godoy, C Catrupay… - International Journal of …, 2023 - mdpi.com
… The incubation program consisted of 95 C for 5 min, followed by 35 cycles of 95 C for 30 s,
57 C for 30 s, 72 C for 30–40 s, and a final extension at 72 C for 5 min. The synthesis of all …

[HTML][HTML] Purinergic P2Y2 and P2X4 receptors are involved in the epithelial-mesenchymal transition and metastatic potential of gastric cancer derived cell lines

…, K Pinto, FG Vázquez-Cuevas, C Coddou - Pharmaceutics, 2021 - mdpi.com
… of 40 cycles consisting of 30 s at 95 C and 60 s at 60 C, detecting fluorescence at the end of
C for 60 s, ramping down to 55 C and then increasing temperature to 95 C by a rate of 0.2 C/…