Endothelial cells in vivo form an interface between flowing blood and vascular tissue,
responding to humoral and physical stimuli to secrete relaxing and contracting factors that …

The preceding chapters establish the primary role of Ca2+ in the activation of smooth
muscle contractile proteins. In this chapter we discuss the Ca2+ transport mechanisms that …

… Loutzenhiser & Van Breemen (26) have recently proposed … Saida & Van Breemen (36) have
compared the sensitivities to … Saida & Van Breemen (39) found the same low sensitivity of …

Thoracic aortic aneurysm (TAA) is the life-threatening complication of Marfan syndrome (MFS),
a connective tissue disorder caused by mutations in the fibrillin-1 gene. TAA is …

β-Blockers, eg, atenolol, are the cornerstone therapy for thoracic aortic aneurysm (TAA) in
patients with Marfan syndrome; however, continued aortic dilatation has been reported. We …

1 We characterized the mechanisms in vascular smooth muscle cells (VSMCs) that produce
asynchronous, wave‐like Ca 2+ oscillations in response to phenylephrine (PE). Confocal …

Impaired angiogenesis could contribute to the increased incidence of coronary and peripheral
artery disease in diabetic patients. Angiogenesis is initiated by vascular endothelial …

… sterile RPMI-1640 medium, stored at 4C, and used fresh for vasomotor function studies on the
… Okon EB, Szado T, Laher I, McManus B, van Breemen C: Augmented contractile response …

The Na + /Ca 2+ exchanger (NCX) is increasingly recognized as a physiological mediator of
Ca 2+ influx and significantly contributes to salt-sensitive hypertension. We recently …

… The temperature program for the amplification was 32 cycles of 1 min at 94C, 1 min at 55C
and 1 min at 72C. The final extension was completed at 72C for 7 min. The RT-PCR products …