[HTML][HTML] Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
Psychedelics produce fast and persistent antidepressant effects and induce neuroplasticity
resembling the effects of clinically approved antidepressants. We recently reported that …
resembling the effects of clinically approved antidepressants. We recently reported that …
Drug interactions at GABAA receptors
ER Korpi, G Gründer, H Lüddens - Progress in neurobiology, 2002 - Elsevier
Neurotransmitter receptor systems have been the focus of intensive pharmacological research
for more than 20 years for basic and applied scientific reasons, but only recently has there …
for more than 20 years for basic and applied scientific reasons, but only recently has there …
Attenuated sensitivity to neuroactive steroids in γ-aminobutyrate type A receptor delta subunit knockout mice
RM Mihalek, PK Banerjee, ER Korpi… - Proceedings of the …, 1999 - National Acad Sciences
γ-Aminobutyric acid (GABA) type A receptors mediate fast inhibitory synaptic transmission
and have been implicated in responses to sedative/hypnotic agents (including neuroactive …
and have been implicated in responses to sedative/hypnotic agents (including neuroactive …
Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior
…, MD Krasowski, CEM Rick, ER Korpi… - Proceedings of the …, 1997 - National Acad Sciences
γ-Aminobutyric acid type A receptors (GABA A -Rs) mediate the bulk of rapid inhibitory synaptic
transmission in the central nervous system. The β3 subunit is an essential component of …
transmission in the central nervous system. The β3 subunit is an essential component of …
Ligand-Gated Ion Channel Subunit Partnerships: GABAAReceptor α6 Subunit Gene Inactivation Inhibits δ Subunit Expression
A Jones, ER Korpi, RM McKernan, R Pelz… - Journal of …, 1997 - Soc Neuroscience
Cerebellar granule cells express six GABA A receptor subunits abundantly (α 1 , α 6 , β 2 , β
3 , γ 2 , and δ) and assemble various pentameric receptor subtypes with unknown subunit …
3 , γ 2 , and δ) and assemble various pentameric receptor subtypes with unknown subunit …
Regulation of GABAA receptor subunit expression by pharmacological agents
M Uusi-Oukari, ER Korpi - Pharmacological reviews, 2010 - ASPET
The γ-aminobutyric acid (GABA) type A receptor system, the main fast-acting inhibitory
neurotransmitter system in the brain, is the pharmacological target for many drugs used clinically …
neurotransmitter system in the brain, is the pharmacological target for many drugs used clinically …
Molecular and pharmacological characterization of GABAA receptor α1 subunit knockout mice
GABA A receptors mediate fast inhibitory neurotransmission in the central nervous system (CNS),
and approximately half of these receptors contain α1 subunits. GABA A receptor α1 …
and approximately half of these receptors contain α1 subunits. GABA A receptor α1 …
Mechanisms of action and persistent neuroplasticity by drugs of abuse
ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - ASPET
Adaptation of the nervous system to different chemical and physiologic conditions is important
for the homeostasis of brain processes and for learning and remembering appropriate …
for the homeostasis of brain processes and for learning and remembering appropriate …
GABA ergic signalling in the immune system
A Barragan, JM Weidner, Z Jin, ER Korpi… - Acta …, 2015 - Wiley Online Library
The GABA ergic system is the main inhibitory neurotransmitter system in the central nervous
system ( CNS ) of vertebrates. Signalling of the transmitter γ‐aminobutyric acid ( GABA ) via …
system ( CNS ) of vertebrates. Signalling of the transmitter γ‐aminobutyric acid ( GABA ) via …
GABAA receptor subtypes as targets for neuropsychiatric drug development
ER Korpi, ST Sinkkonen - Pharmacology & therapeutics, 2006 - Elsevier
The main inhibitory neurotransmitter system in the brain, the γ-aminobutyric acid (GABA)
system, is the target for many clinically used drugs to treat, for example, anxiety disorders and …
system, is the target for many clinically used drugs to treat, for example, anxiety disorders and …