International Union of Pharmacology. XIII. Classification of histamine receptors

SJ Hill, CR Ganellin, H Timmerman, JC Schwartz… - Pharmacological …, 1997 - ASPET
The classification of histamine receptors has to date been based on rigorous classical
pharmacological analysis, and as yet, the classification of the three histamine receptors that have …

Monostrain, multistrain and multispecies probiotics—A comparison of functionality and efficacy

HM Timmerman, CJM Koning, L Mulder… - International journal of …, 2004 - Elsevier
This literature review was carried out to make a comparison of functionality and efficacy
between monostrain, multistrain and multispecies probiotics. A monostrain probiotic is defined …

Molecular pharmacological aspects of histamine receptors

R Leurs, MJ Smit, H Timmerman - Pharmacology & therapeutics, 1995 - Elsevier
In this article, we review the recent developments in the field of histamine research. Besides
the description of pharmacological tools for the H 1 , H 2 and H 3 receptor, specific attention …

Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial

…, MA Boermeester, H van Goor, HM Timmerman… - The Lancet, 2008 - thelancet.com
… acute pancreatitis (Acute Physiology and Chronic Health Evaluation [APACHE II] score ≥8,
Imrie score ≥3, or C-reactive protein >150 mg/L) were randomly assigned within 72 h of …

Iron fortification adversely affects the gut microbiome, increases pathogen abundance and induces intestinal inflammation in Kenyan infants

…, HM Timmerman, DW Swinkels, H Tjalsma… - Gut, 2015 - gut.bmj.com
Background In-home iron fortification for infants in developing countries is recommended for
control of anaemia, but low absorption typically results in >80% of the iron passing into the …

[HTML][HTML] Health and growth of veal calves fed milk replacers with or without probiotics

HM Timmerman, L Mulder, H Everts… - Journal of Dairy …, 2005 - Elsevier
Four experiments with 1-wk-old veal calves were conducted to assess the influence of
probiotics on growth and health indicators. In experiments 1 and 2, the liquid probiotic …

[HTML][HTML] The histamine H3 receptor: from gene cloning to H3 receptor drugs

R Leurs, RA Bakker, H Timmerman… - Nature reviews Drug …, 2005 - nature.com
… For both H 3 receptor agonists and H 3 receptor inverse agonists/antagonists, interesting
activities in several preclinical models of important human diseases, including obesity, migraine…

[BOOK][B] Lipophilicity in drug action and toxicology

…, R Mannhold, H Kubinyi, H Timmerman - 1996 - bookland.ru
After three volumes covering the various techniques quantifying the relations of biological
activity and chemical properties of drug molecules, the fourth volume in the series “Methods …

Impairment of immune function in harbor seals (Phoca vitulina) feeding on fish from polluted waters

…, H Timmerman, S Heisterkamp, H Van Loveren… - Ambio, 1994 - repub.eur.nl
Disease outbreaks with high mortality rates among seals and dolphins have recently attracted
considerable public and scientific interest. Allhouyh in most cases morbillivirus infections …

The effects of selected probiotic strains on the development of eczema (the PandA study)

…, F Sengers, H Timmerman, N Van Uden, H Smidt… - Allergy, 2009 - Wiley Online Library
… 72 h. Cytokines were detected in supernatants by multiplex assay (Luminex) as previously
described in detail (23). H … Supernatants were collected at 48 h and 72 h and cytokines were …