Pleiotropic effects of statins
JK Liao, U Laufs - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract Statins are potent inhibitors of cholesterol biosynthesis. In clinical trials, statins are
beneficial in the primary and secondary prevention of coronary heart disease. However, the …
beneficial in the primary and secondary prevention of coronary heart disease. However, the …
Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
M Takemoto, JK Liao - Arteriosclerosis, thrombosis, and vascular …, 2001 - Am Heart Assoc
The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors or statins are potent inhibitors
of cholesterol biosynthesis. Several large clinical trials have demonstrated the beneficial …
of cholesterol biosynthesis. Several large clinical trials have demonstrated the beneficial …
Pleiotropic effects of statins on the cardiovascular system
A Oesterle, U Laufs, JK Liao - Circulation research, 2017 - Am Heart Assoc
The statins have been used for 30 years to prevent coronary artery disease and stroke. Their
primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic …
primary mechanism of action is the lowering of serum cholesterol through inhibiting hepatic …
[HTML][HTML] Observation of a new boson at a mass of 125 GeV with the CMS experiment at the LHC
…, G Grégoire, J Hollar, V Lemaitre, J Liao… - Physics Letters B, 2012 - Elsevier
Results are presented from searches for the standard model Higgs boson in proton–proton
collisions at s=7 and 8 TeV in the Compact Muon Solenoid experiment at the LHC, using …
collisions at s=7 and 8 TeV in the Compact Muon Solenoid experiment at the LHC, using …
Cisplatin and radiotherapy with or without erlotinib in locally advanced squamous cell carcinoma of the head and neck: a randomized phase II trial
…, F Yunus, BF Kurland, KD Eaton, JJ Liao… - Journal of clinical …, 2013 - ascopubs.org
Purpose The combination of cisplatin and radiotherapy is a standard treatment for patients
with locally advanced squamous cell carcinoma of the head and neck (SCCHN). Cetuximab-…
with locally advanced squamous cell carcinoma of the head and neck (SCCHN). Cetuximab-…
Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records
…, X Yu, W Zhang, J Li, D Zhao, D Xu, Q Gong, J Liao… - The lancet, 2020 - thelancet.com
Background Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus
disease (COVID-19) were based on information from the general population. Limited …
disease (COVID-19) were based on information from the general population. Limited …
Specific inhibition of Stat3 signal transduction by PIAS3
CD Chung, J Liao, B Liu, X Rao, P Jay, P Berta… - Science, 1997 - science.org
The signal transducer and activator of transcription–3 (Stat3) protein is activated by the
interleukin 6 (IL-6) family of cytokines, epidermal growth factor, and leptin. A protein named …
interleukin 6 (IL-6) family of cytokines, epidermal growth factor, and leptin. A protein named …
[HTML][HTML] Observation of a new boson with mass near 125 GeV in pp collisions at and 8 TeV
…, A Giammanco, J Hollar, V Lemaitre, J Liao… - Journal of High Energy …, 2013 - Springer
A detailed description is reported of the analysis used by the CMS Collaboration in the
search for the standard model Higgs boson in pp collisions at the LHC, which led to the …
search for the standard model Higgs boson in pp collisions at the LHC, which led to the …
Cutting edge: 1, 25-dihydroxyvitamin D3 is a direct inducer of antimicrobial peptide gene expression
…, V Bourdeau, Y Nagai, Q Wang, J Liao… - The Journal of …, 2004 - journals.aai.org
The hormonal form of vitamin D 3, 1, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), is an immune
system modulator and induces expression of the TLR coreceptor CD14. 1, 25 (OH) 2 D 3 …
system modulator and induces expression of the TLR coreceptor CD14. 1, 25 (OH) 2 D 3 …
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
Background—Oxidized low-density lipoprotein (ox-LDL) causes endothelial dysfunction in
part by decreasing the availability of endothelial nitric oxide (NO). Although HMG CoA …
part by decreasing the availability of endothelial nitric oxide (NO). Although HMG CoA …