The γ-aminobutyric acid (GABA) type A receptor system, the main fast-acting inhibitory
neurotransmitter system in the brain, is the pharmacological target for many drugs used clinically …

GABA is the major inhibitory neurotransmitter in the central nervous system (CNS). The type
A GABA receptor (GABA A R) system is the primary pharmacological target for many drugs …

INTRODUCTION/AIMS: The use of cathinone-derivative designer drugs methylone and
mephedrone has increased rapidly in recent years. Our aim was to investigate the possible long-…

AMPA-type glutamate receptors have been suggested to be involved in the neurobiological
mechanisms of drug addiction. We have made use of two mouse lines, which both have …

Benzodiazepine‐ and alcohol‐induced ataxias in rodents have been proposed to be affected
by the γ‐aminobutyric acid type A (GABA A ) receptor α6 subunit, which contributes to …

Humulus lupulus L. (hops) is a major constituent of beer. It exhibits neuroactive properties
that make it useful as a sleeping aid. These effects are hypothesized to be mediated by an …

Hops are a major component of beer that is added during brewing. In addition to its wide
range of bioactivity, it exhibits neuroactive properties as a sedative and sleeping aid. The …

The main fast-acting inhibitory receptors in the mammalian brain are γ-aminobutyric acid
type-A (GABA A) receptors for which neurosteroids, a subclass of steroids synthesized de novo …

Impairment of excretion and enzymatic processing of nitrogen, for example, because of liver
or kidney failure, or with urea cycle and creatine synthesis enzyme defects, surprisingly …

We have generated several transgenic mouse lines and rabbits expressing efficiently (up to
0.3 mg/ml in mice and up to 0.5 mg/ml in rabbits) human erythropoietin in their milk as …