User profiles for P. Ferdinandy

Péter Ferdinandy

Semmelweis University, Budapest; Pharmahungary Group, Szeged, Hungary
Verified email at pharmahungary.com
Cited by 23605

Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning

P Ferdinandy, R Schulz, GF Baxter - Pharmacological reviews, 2007 - ASPET
Therapeutic strategies to protect the ischemic myocardium have been studied extensively.
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …

Interaction of risk factors, comorbidities, and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote …

P Ferdinandy, DJ Hausenloy, G Heusch… - Pharmacological …, 2014 - ASPET
Pre-, post-, and remote conditioning of the myocardium are well described adaptive
responses that markedly enhance the ability of the heart to withstand a prolonged ischemia/…

Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia‐reperfusion injury and preconditioning

P Ferdinandy, R Schulz - British journal of pharmacology, 2003 - Wiley Online Library
There appears to be a controversy in the study of myocardial ischaemia‐reperfusion injury
and preconditioning whether nitric oxide (NO) plays a protective or detrimental role. A number …

[HTML][HTML] Isolation of exosomes from blood plasma: qualitative and quantitative comparison of ultracentrifugation and size exclusion chromatography methods

…, V Kumar, P Nagy, Á Kittel, EI Buzás, P Ferdinandy… - PloS one, 2015 - journals.plos.org
… Statistical significance was accepted if p<0.05. … of exosomal isolates after serial UC of the
supernatant with 1h UC at 4C (B; n = 3; p>0.05), with 10-fold dilution at 4C (C, top), with smaller …

Heat shock proteins as emerging therapeutic targets

…, L Vígh, P Csermely, P Ferdinandy - British journal of …, 2005 - Wiley Online Library
Chaperones (stress proteins) are essential proteins to help the formation and maintenance
of the proper conformation of other proteins and to promote cell survival after a large variety …

Drug-induced mitochondrial dysfunction and cardiotoxicity

…, P Ferdinandy, L Liaudet, P Pacher - American Journal of …, 2015 - journals.physiology.org
Mitochondria has an essential role in myocardial tissue homeostasis; thus deterioration in
mitochondrial function eventually leads to cardiomyocyte and endothelial cell death and …

Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European …

…, GF Baxter, F Di Lisa, P Ferdinandy… - Cardiovascular …, 2010 - academic.oup.com
Ischaemic postconditioning (brief periods of ischaemia alternating with brief periods of
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …

[HTML][HTML] Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

…, C Wilder, DM Yellon, P Ferdinandy… - Basic research in …, 2018 - Springer
The potential for ischemic preconditioning to reduce infarct size was first recognized more
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing [460] …

Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure

P Ferdinandy, H Danial, I Ambrus, RA Rothery… - Circulation …, 2000 - Am Heart Assoc
… Major sources of superoxide in the rat heart include the XOR system 16 and NAD(P)H
oxidoreductases. Our results show that cytokines rapidly increased myocardial activities of XO and …

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week

SM Davidson, P Ferdinandy, I Andreadou… - Journal of the American …, 2019 - jacc.org
Many treatments have been identified that confer robust cardioprotection in experimental
animal models of acute ischemia and reperfusion injury. However, translation of these …