User profiles for P. Ferdinandy
Péter FerdinandySemmelweis University, Budapest; Pharmahungary Group, Szeged, Hungary Verified email at pharmahungary.com Cited by 23605 |
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning
Therapeutic strategies to protect the ischemic myocardium have been studied extensively.
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …
Interaction of risk factors, comorbidities, and comedications with ischemia/reperfusion injury and cardioprotection by preconditioning, postconditioning, and remote …
Pre-, post-, and remote conditioning of the myocardium are well described adaptive
responses that markedly enhance the ability of the heart to withstand a prolonged ischemia/…
responses that markedly enhance the ability of the heart to withstand a prolonged ischemia/…
Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia‐reperfusion injury and preconditioning
P Ferdinandy, R Schulz - British journal of pharmacology, 2003 - Wiley Online Library
There appears to be a controversy in the study of myocardial ischaemia‐reperfusion injury
and preconditioning whether nitric oxide (NO) plays a protective or detrimental role. A number …
and preconditioning whether nitric oxide (NO) plays a protective or detrimental role. A number …
[HTML][HTML] Isolation of exosomes from blood plasma: qualitative and quantitative comparison of ultracentrifugation and size exclusion chromatography methods
… Statistical significance was accepted if p<0.05. … of exosomal isolates after serial UC of the
supernatant with 1h UC at 4C (B; n = 3; p>0.05), with 10-fold dilution at 4C (C, top), with smaller …
supernatant with 1h UC at 4C (B; n = 3; p>0.05), with 10-fold dilution at 4C (C, top), with smaller …
Heat shock proteins as emerging therapeutic targets
Chaperones (stress proteins) are essential proteins to help the formation and maintenance
of the proper conformation of other proteins and to promote cell survival after a large variety …
of the proper conformation of other proteins and to promote cell survival after a large variety …
Drug-induced mitochondrial dysfunction and cardiotoxicity
…, P Ferdinandy, L Liaudet, P Pacher - American Journal of …, 2015 - journals.physiology.org
Mitochondria has an essential role in myocardial tissue homeostasis; thus deterioration in
mitochondrial function eventually leads to cardiomyocyte and endothelial cell death and …
mitochondrial function eventually leads to cardiomyocyte and endothelial cell death and …
Postconditioning and protection from reperfusion injury: where do we stand? Position paper from the Working Group of Cellular Biology of the Heart of the European …
…, GF Baxter, F Di Lisa, P Ferdinandy… - Cardiovascular …, 2010 - academic.oup.com
Ischaemic postconditioning (brief periods of ischaemia alternating with brief periods of
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …
[HTML][HTML] Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection
…, C Wilder, DM Yellon, P Ferdinandy… - Basic research in …, 2018 - Springer
The potential for ischemic preconditioning to reduce infarct size was first recognized more
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing [460] …
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing [460] …
Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure
P Ferdinandy, H Danial, I Ambrus, RA Rothery… - Circulation …, 2000 - Am Heart Assoc
… Major sources of superoxide in the rat heart include the XOR system 16 and NAD(P)H
oxidoreductases. Our results show that cytokines rapidly increased myocardial activities of XO and …
oxidoreductases. Our results show that cytokines rapidly increased myocardial activities of XO and …
Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury: JACC Review Topic of the Week
Many treatments have been identified that confer robust cardioprotection in experimental
animal models of acute ischemia and reperfusion injury. However, translation of these …
animal models of acute ischemia and reperfusion injury. However, translation of these …