The neurobiology of slow synaptic transmission

P Greengard - Science, 2001 - science.org
Nerve cells communicate with each other through two mechanisms, referred to as fast and
slow synaptic transmission. Fast-acting neurotransmitters, eg, glutamate (excitatory) and γ-…

Synaptic vesicle phosphoproteins and regulation of synaptic function

P Greengard, F Valtorta, AJ Czernik, F Benfenati - Science, 1993 - science.org
Complex brain functions, such as learning and memory, are believed to involve changes in
the efficiency of communication between nerve cells. Therefore, the elucidation of the …

[PDF][PDF] Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade

P Greengard, PB Allen, AC Nairn - Neuron, 1999 - cell.com
… DopaminerSnyder, GL, Fisone, G., Morino, P., Gundersen, V., Ottersen, OP, gic modulation
of neuronal excitability in the striatum and nucleus Hokfelt, T., and Greengard, P. (1993). …

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation.

…, W Schiebler, P Greengard, P De Camilli - The Journal of cell …, 1983 - rupress.org
… Huttner, WB, LJ DeGermaro, and P. Greengard. 1981. Differential phosphorylatinn of
multiple sites in purified protein I by cyclic AMP-dependent and calcium-dependent …

Regulation of NMDA receptor trafficking by amyloid-β

…, PJ Lombroso, GK Gouras, P Greengard - Nature …, 2005 - nature.com
… Shepherd and members of the Greengard and Gouras labs for helpful discussions. This
work was supported by the Fisher Foundation for Alzheimer's Research, US National Institutes …

Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline

…, R Mohs, KL Davis, P Davies, P Greengard… - Jama, 2000 - jamanetwork.com
… Differences were considered significant at a P value of <.05, after correction for multiple
testing using the Bonferroni method. Because of the heterogeneity of variance between groups …

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

N Sato, L Meijer, L Skaltsounis, P Greengard… - Nature medicine, 2004 - nature.com
Human and mouse embryonic stem cells (HESCs and MESCs, respectively) self-renew
indefinitely while maintaining the ability to generate all three germ-layer derivatives. Despite the …

[HTML][HTML] Intraneuronal Aβ42 accumulation in human brain

…, JD Buxbaum, H Xu, P Greengard… - The American journal of …, 2000 - Elsevier
Alzheimer's disease (AD) is characterized by the deposition of senile plaques (SPs) and
neurofibrillary tangles (NFTs) in vulnerable brain regions. SPs are composed of aggregated β-…

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. I. Its general distribution in synapses of the central and peripheral nervous system demonstrated by …

P De Camilli, R Cameron, P Greengard - The Journal of cell biology, 1983 - rupress.org
Synapsin I (formerly referred to as protein I) is the collective name for two almost identical
phosphoproteins, synapsin Ia and synapsin Ib (protein Ia and protein Ib), present in the …

DARPP-32, a dopamine-and adenosine 3': 5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical …

…, HC Hemmings, SI Walaas, P Greengard - Journal of …, 1984 - Soc Neuroscience
Immunocytochemical studies have been carried out to determine the regional and cellular
distribution of DARPP-32, a protein the phosphorylation of which can be regulated by …