Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily
SA Marchitti, C Brocker, D Stagos… - Expert opinion on drug …, 2008 - Taylor & Francis
Background: Aldehydes are highly reactive molecules. While several non-P450 enzyme
systems participate in their metabolism, one of the most important is the aldehyde …
systems participate in their metabolism, one of the most important is the aldehyde …
Neurotoxicity and metabolism of the catecholamine-derived 3, 4-dihydroxyphenylacetaldehyde and 3, 4-dihydroxyphenylglycolaldehyde: the role of aldehyde …
SA Marchitti, RA Deitrich, V Vasiliou - Pharmacological reviews, 2007 - ASPET
… Marchitti, Richard A. Deitrich and Vasilis Vasiliou …
Relationships of chemical concentrations in maternal and cord blood: a review of available data
…, SM Hays, CR Kirman, SA Marchitti… - Journal of Toxicology …, 2014 - Taylor & Francis
The developing fetus is likely to be exposed to the same environmental chemicals as the
mother during critical periods of growth and development. The degree of maternal–fetal transfer …
mother during critical periods of growth and development. The degree of maternal–fetal transfer …
Environmental chemicals in breast milk and formula: exposure and risk assessment implications
…, MH Davis, EP Hines, SA Marchitti… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Human health risk assessment methods have advanced in recent years to more
accurately estimate risks associated with exposure during childhood. However, predicting …
accurately estimate risks associated with exposure during childhood. However, predicting …
Current breast milk PFAS levels in the United States and Canada: after all this time, why don't we know more?
…, H Goeden, DQ Naiman, SA Marchitti… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Despite 20 y of biomonitoring studies of per- and polyfluoroalkyl substances (PFAS)
in both serum and urine, we have an extremely limited understanding of PFAS …
in both serum and urine, we have an extremely limited understanding of PFAS …
Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes
SA Marchitti, Y Chen, DC Thompson… - Eye & contact lens, 2011 - journals.lww.com
Solar ultraviolet radiation (UVR) exposes the human eye to near constant oxidative stress.
Evidence suggests that UVR is the most important environmental insult leading to the …
Evidence suggests that UVR is the most important environmental insult leading to the …
Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature
WJ Black, D Stagos, SA Marchitti… - Pharmacogenetics …, 2009 - journals.lww.com
Objective The human aldehyde dehydrogenase (ALDH) gene superfamily consists of 19
genes encoding enzymes critical for NAD (P)+-dependent oxidation of endogenous and …
genes encoding enzymes critical for NAD (P)+-dependent oxidation of endogenous and …
Human and rat ABC transporter efflux of bisphenol a and bisphenol a glucuronide: interspecies comparison and implications for pharmacokinetic assessment
CS Mazur, SA Marchitti, M Dimova… - Toxicological …, 2012 - academic.oup.com
Significant interspecies differences exist between human and rodent with respect to
absorption, distribution, and excretion of bisphenol A (BPA) and its primary metabolite, BPA-…
absorption, distribution, and excretion of bisphenol A (BPA) and its primary metabolite, BPA-…
Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues
SA Marchitti, DJ Orlicky, C Brocker… - … of Histochemistry & …, 2010 - journals.sagepub.com
… and does not crossreact with other ALDH isoforms (Marchitti et al. 2007b). Briefly, a …
Immunoblots demonstrating the efficacy of this antibody have been published (Marchitti et al…
Immunoblots demonstrating the efficacy of this antibody have been published (Marchitti et al…
Molecular characterization, expression analysis, and role of ALDH3B1 in the cellular protection against oxidative stress
SA Marchitti, C Brocker, DJ Orlicky, V Vasiliou - Free Radical Biology and …, 2010 - Elsevier
Aldehyde dehydrogenase (ALDH) enzymes are critical in the detoxification of aldehydes.
The human genome contains 19 ALDH genes, mutations in which are the basis of several …
The human genome contains 19 ALDH genes, mutations in which are the basis of several …