The physiology, pathology, and pharmacology of voltage-gated calcium channels and their future therapeutic potential
GW Zamponi, J Striessnig, A Koschak… - Pharmacological …, 2015 - ASPET
Voltage-gated calcium channels are required for many key functions in the body. In this
review, the different subtypes of voltage-gated calcium channels are described and their …
review, the different subtypes of voltage-gated calcium channels are described and their …
Mammalian G proteins and their cell type specific functions
N Wettschureck, S Offermanns - Physiological reviews, 2005 - journals.physiology.org
Heterotrimeric G proteins are key players in transmembrane signaling by coupling a huge
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …
variety of receptors to channel proteins, enzymes, and other effector molecules. Multiple …
Presynaptic calcium channels: specialized control of synaptic neurotransmitter release
AC Dolphin, A Lee - Nature Reviews Neuroscience, 2020 - nature.com
Chemical synapses are heterogeneous junctions formed between neurons that are
specialized for the conversion of electrical impulses into the exocytotic release of …
specialized for the conversion of electrical impulses into the exocytotic release of …
International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy
MP Abbracchio, G Burnstock, JM Boeynaems… - Pharmacological …, 2006 - ASPET
There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …
signaling since the last review published by our International Union of Pharmacology …
Voltage‐gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology
AC Dolphin - The Journal of physiology, 2016 - Wiley Online Library
Voltage‐gated calcium channels are essential players in many physiological processes in
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …
Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond
AC Dolphin - Nature Reviews Neuroscience, 2012 - nature.com
The voltage-gated calcium channel α2δ and β subunits are traditionally considered to be
auxiliary subunits that enhance channel trafficking, increase the expression of functional …
auxiliary subunits that enhance channel trafficking, increase the expression of functional …
The β Subunit of Voltage-Gated Ca2+ Channels
Calcium regulates a wide spectrum of physiological processes such as heartbeat, muscle
contraction, neuronal communication, hormone release, cell division, and gene …
contraction, neuronal communication, hormone release, cell division, and gene …
Calcium-permeable ion channels in pain signaling
The detection and processing of painful stimuli in afferent sensory neurons is critically
dependent on a wide range of different types of voltage-and ligand-gated ion channels …
dependent on a wide range of different types of voltage-and ligand-gated ion channels …
Structure of a complex between a voltage-gated calcium channel β-subunit and an α-subunit domain
F Van Petegem, KA Clark, FC Chatelain, DL Minor Jr - Nature, 2004 - nature.com
Voltage-gated calcium channels (CaVs) govern muscle contraction, hormone and
neurotransmitter release, neuronal migration, activation of calcium-dependent signalling …
neurotransmitter release, neuronal migration, activation of calcium-dependent signalling …
Supramolecular assemblies and localized regulation of voltage-gated ion channels
S Dai, DD Hall, JW Hell - Physiological reviews, 2009 - journals.physiology.org
This review addresses the localized regulation of voltage-gated ion channels by
phosphorylation. Comprehensive data on channel regulation by associated protein kinases …
phosphorylation. Comprehensive data on channel regulation by associated protein kinases …