Role of Pharmacokinetics and Metabolism in Drug Discovery and Development

Jiunn H. Lin; Anthony Y. H. Lu

Article Information

vol. 49 no. 4 403-449

PubMed

9443165

Published By

American Society for Pharmacology and Experimental Therapeutics

Print ISSN

0031-6997

Online ISSN

1521-0081

History

Published online December 1, 1997.

The American Society for Pharmacology and Experimental Therapeutics

Author Information

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Article usage

Article usage: January 1999 to October 2021

	Abstract	Full	Pdf
Jan 1999	38	125	86
Feb 1999	32	201	92
Mar 1999	31	134	45
Apr 1999	32	98	65
May 1999	22	81	46
Jun 1999	29	87	28
Jul 1999	21	92	49
Aug 1999	25	96	56
Sep 1999	17	114	63
Oct 1999	47	141	78
Nov 1999	44	146	55
Dec 1999	26	206	210
Jan 2000	22	116	62
Feb 2000	33	184	62
Mar 2000	34	139	82
Apr 2000	31	104	71
May 2000	21	119	63
Jun 2000	19	91	75
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Aug 2000	23	71	53
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Oct 2000	30	100	66
Nov 2000	26	104	115
Dec 2000	19	50	70
Jan 2001	31	76	156
Feb 2001	35	94	104
Mar 2001	46	97	102
Apr 2001	40	65	78
May 2001	22	53	84
Jun 2001	21	85	110
Jul 2001	23	48	85
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Nov 2001	27	83	83
Dec 2001	25	65	85
Jan 2002	36	60	89
Feb 2002	20	87	100
Mar 2002	29	99	116
Apr 2002	28	102	120
May 2002	36	83	260
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Jul 2002	23	96	171
Aug 2002	22	69	125
Sep 2002	26	77	152
Oct 2002	43	138	141
Nov 2002	31	143	170
Dec 2002	31	86	144
Jan 2003	35	72	163
Feb 2003	46	128	153
Mar 2003	38	114	188
Apr 2003	25	102	177
May 2003	38	56	134
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Aug 2003	40	233	203
Sep 2003	52	364	205
Oct 2003	58	463	205
Nov 2003	59	546	169
Dec 2003	49	420	135
Jan 2004	65	418	167
Feb 2004	71	576	188
Mar 2004	98	828	226
Apr 2004	71	708	209
May 2004	99	699	282
Jun 2004	59	677	301
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Aug 2004	71	732	394
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Jan 2005	136	975	301
Feb 2005	96	702	282
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Jan 2006	123	455	216
Feb 2006	93	471	181
Mar 2006	125	476	214
Apr 2006	116	348	191
May 2006	147	255	189
Jun 2006	126	219	168
Jul 2006	111	189	139
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Oct 2006	193	480	300
Nov 2006	221	558	313
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Jan 2007	170	550	257
Feb 2007	171	432	255
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Oct 2007	158	320	260
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Oct 2008	185	250	193
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Feb 2009	148	159	165
Mar 2009	248	220	201
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Jun 2009	205	171	145
Jul 2009	167	135	159
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Oct 2009	222	158	228
Nov 2009	175	121	128
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Jan 2010	2	89	111
Feb 2010	0	64	80
Mar 2010	7	99	85
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Jun 2010	3	191	71
Jul 2010	0	291	116
Aug 2010	0	322	97
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Oct 2010	9	390	124
Nov 2010	4	347	127
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Mar 2011	80	459	173
Apr 2011	45	488	161
May 2011	0	599	173
Jun 2011	0	423	142
Jul 2011	0	445	146
Aug 2011	0	771	246
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Oct 2011	0	1560	508
Nov 2011	0	1781	455
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Jan 2012	0	1959	299
Feb 2012	0	2012	399
Mar 2012	0	2129	388
Apr 2012	0	1233	296
May 2012	0	1332	274
Jun 2012	0	912	282
Jul 2012	0	953	263
Aug 2012	0	929	263
Sep 2012	0	1130	333
Oct 2012	0	1574	293
Nov 2012	0	1460	323
Dec 2012	0	1153	184
Jan 2013	0	910	183
Feb 2013	0	1066	189
Mar 2013	0	1597	274
Apr 2013	0	1535	261
May 2013	0	1133	281
Jun 2013	0	985	232
Jul 2013	0	1473	234
Aug 2013	0	1527	257
Sep 2013	0	2178	321
Oct 2013	0	3003	401
Nov 2013	0	3552	379
Dec 2013	0	2229	249
Jan 2014	0	2056	326
Feb 2014	0	2192	318
Mar 2014	0	2452	463
Apr 2014	0	2972	408
May 2014	0	3287	350
Jun 2014	0	1932	270
Jul 2014	0	1881	210
Aug 2014	0	1627	171
Sep 2014	0	1531	172
Oct 2014	0	1537	175
Nov 2014	0	1787	224
Dec 2014	0	1686	201
Jan 2015	0	2199	320
Feb 2015	0	1758	207
Mar 2015	0	2308	303
Apr 2015	0	1890	278
May 2015	0	2017	296
Jun 2015	0	1605	222
Jul 2015	0	1521	205
Aug 2015	0	1592	165
Sep 2015	0	1629	178
Oct 2015	0	2518	199
Nov 2015	0	2118	211
Dec 2015	0	1480	173
Jan 2016	0	1364	156
Feb 2016	0	1450	175
Mar 2016	0	1137	207
Apr 2016	0	486	143
May 2016	0	407	99
Jun 2016	0	352	74
Jul 2016	0	235	57
Aug 2016	0	365	55
Sep 2016	0	309	85
Oct 2016	0	426	87
Nov 2016	0	1094	145
Dec 2016	0	840	99
Jan 2017	0	555	108
Feb 2017	0	670	136
Mar 2017	0	670	138
Apr 2017	0	305	106
May 2017	0	221	156
Jun 2017	0	208	111
Jul 2017	0	186	145
Aug 2017	0	238	111
Sep 2017	0	308	92
Oct 2017	0	335	105
Nov 2017	0	345	141
Dec 2017	0	174	80
Jan 2018	0	167	127
Feb 2018	0	258	113
Mar 2018	0	271	115
Apr 2018	0	356	115
May 2018	0	267	81
Jun 2018	0	250	63
Jul 2018	0	186	58
Aug 2018	0	191	59
Sep 2018	0	195	40
Oct 2018	0	343	44
Nov 2018	0	400	78
Dec 2018	0	86	26
Jan 2019	0	17	17
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May 2019	0	14	12
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May 2020	0	16	15
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Jul 2020	0	5	7
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May 2021	0	16	14
Jun 2021	0	36	8
Jul 2021	0	10	8
Aug 2021	0	23	12
Sep 2021	0	21	16
Oct 2021	0	14	4