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Review ArticleReview

Role of Pharmacokinetics and Metabolism in Drug Discovery and Development

Jiunn H. Lin and Anthony Y. H. Lu
Pharmacological Reviews December 1997, 49 (4) 403-449;
Jiunn H. Lin
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Anthony Y. H. Lu
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Article Information

vol. 49 no. 4 403-449
PubMed 
9443165

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online December 1, 1997.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jiunn H. LinFNa and
  2. Anthony Y. H. Lu
  1. Department of Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania

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    Pharmacological Reviews
    Vol. 49, Issue 4
    1 Dec 1997
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    Review ArticleReview

    Role of Pharmacokinetics and Metabolism in Drug Discovery and Development

    Jiunn H. Lin and Anthony Y. H. Lu
    Pharmacological Reviews December 1, 1997, 49 (4) 403-449;

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    Review ArticleReview

    Role of Pharmacokinetics and Metabolism in Drug Discovery and Development

    Jiunn H. Lin and Anthony Y. H. Lu
    Pharmacological Reviews December 1, 1997, 49 (4) 403-449;
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    Jump to section

    • Article
      • I. Introduction
      • II. Role of Pharmacokinetics and Metabolism in Drug Design
      • III. Role of Metabolism in Drug Toxicity
      • IV. Role of Pharmacokinetics and Metabolism in Drug Development
      • V. Interindividual Variability: A Critical Issue in Drug Development
      • VI. Conclusions
      • Footnotes
      • References
    • Figures & Data
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