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- Article
- I. Introduction
- II. Consumption and Metabolism of Caffeine
- III. Molecular and Cellular Action of Caffeine in the Brain
- IV. Actions of Caffeine on Brain Functions and Behavior
- V. Addiction and Drug Dependence
- VI. Caffeine Withdrawal and Relief of Abstinence Symptoms by Caffeine
- VII. Tolerance to the Effects of Caffeine
- VIII. Caffeine Discrimination and Dose Adjustment in Animals and Humans
- IX. Reinforcing Effects of Caffeine
- X. Possible Reinforcing Effects of Coffee, Independent of Caffeine Content
- XI. Comparisons with Known Addictive Compounds and Interactions between Caffeine and Addictive Drugs
- XII. Possible Harmful Effects of Caffeine at the Individual or Social Level—Abuse or Misuse
- XIII. Conclusions
- Acknowledgments
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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