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Review ArticleReview

Vanilloid (Capsaicin) Receptors and Mechanisms

Arpad Szallasi and Peter M. Blumberg
Pharmacological Reviews June 1999, 51 (2) 159-212;
Arpad Szallasi
Molecular Mechanisms of Tumor Promotion Section, Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, Bethesda, Maryland
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Peter M. Blumberg
Molecular Mechanisms of Tumor Promotion Section, Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, Bethesda, Maryland
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Article Information

vol. 51 no. 2 159-212
PubMed 
10353985

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online June 1, 1999.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Arpad Szallasi1 and
  2. Peter M. Blumberg
  1. Molecular Mechanisms of Tumor Promotion Section, Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, Bethesda, Maryland

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In this issue

Pharmacological Reviews: 51 (2)
Pharmacological Reviews
Vol. 51, Issue 2
1 Jun 1999
  • Table of Contents
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Review ArticleReview

Vanilloid (Capsaicin) Receptors and Mechanisms

Arpad Szallasi and Peter M. Blumberg
Pharmacological Reviews June 1, 1999, 51 (2) 159-212;

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Review ArticleReview

Vanilloid (Capsaicin) Receptors and Mechanisms

Arpad Szallasi and Peter M. Blumberg
Pharmacological Reviews June 1, 1999, 51 (2) 159-212;
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  • Article
    • I. Foreword: A Brief History of a Really “Hot” Aspect of Pharmacology
    • II. Introduction
    • III. Direct Evidence for a Vanilloid (Capsaicin) Receptor
    • IV. Anatomical Localization and Tissue Specificity of VRs
    • V. Evidence for Multiple VRs
    • VI. Biochemical Pharmacology of VRs
    • VII. Requirements for Ligand Recognition by VRs: Typical and Novel Vanilloids
    • VIII. Vanilloid Mechanisms
    • IX. Diverse Biological Actions of Vanilloids; VR-Mediated and Independent Mechanism
    • X. Species-Related Differences in Vanilloid Actions
    • XI. Endogenous Vanilloids: Do They Exist?
    • XII. Vanilloids in Clinical Practice: Current Uses and Future Perspectives
    • XIII. Vanilloids: Carcinogens, Anticarcinogens, or Neither?
    • XIV. Concluding Remarks, Emerging Principles, and Future Perspectives
    • Acknowledgments
    • Appendix
    • Note Added in Proof.
    • Footnotes
    • Abbreviations
    • References
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