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Review ArticleReview

Yeast Mutants As a Model System for Identification of Determinants of Chemosensitivity

Paola Perego, Gretchen S. Jimenez, Laura Gatti, Stephen B. Howell and Franco Zunino
Pharmacological Reviews December 2000, 52 (4) 477-492;
Paola Perego
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Gretchen S. Jimenez
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Article Information

vol. 52 no. 4 477-492

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online December 1, 2000.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Paola Perego1,1,
  2. Gretchen S. Jimenez2,
  3. Laura Gatti1,
  4. Stephen B. Howell3, and
  5. Franco Zunino1
  1. 1Istituto Nazionale Tumori, Milan, Italy (P.P., L.G., F.Z.); 2Vical Inc., San Diego, California (G.S.J.); and 3Department of Medicine and the Cancer Center, University of California, San Diego, La Jolla, California (S.B.H.)
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Pharmacological Reviews: 52 (4)
Pharmacological Reviews
Vol. 52, Issue 4
1 Dec 2000
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Review ArticleReview

Yeast Mutants As a Model System for Identification of Determinants of Chemosensitivity

Paola Perego, Gretchen S. Jimenez, Laura Gatti, Stephen B. Howell and Franco Zunino
Pharmacological Reviews December 1, 2000, 52 (4) 477-492;

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Review ArticleReview

Yeast Mutants As a Model System for Identification of Determinants of Chemosensitivity

Paola Perego, Gretchen S. Jimenez, Laura Gatti, Stephen B. Howell and Franco Zunino
Pharmacological Reviews December 1, 2000, 52 (4) 477-492;
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  • Article
    • Abstract
    • I. Introduction
    • II. Integrating Model Systems for Antitumor Pharmacology Studies
    • III. Relevant Features of Yeast Cells
    • IV. Use of Yeast Rad Mutants to Study Drug Mechanisms
    • V. Rationale for Using Yeast As a Model System
    • VI. Molecular Pathways Regulating DNA Damage Responses
    • VII. Conclusions
    • Acknowledgments
    • Footnotes
    • Abbreviations
    • References
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  • International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology
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