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- Published online December 1, 2000.
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The American Society for Pharmacology and Experimental Therapeutics
Author Information
- 1Inflammatory Joint Diseases Section, Arthritis and Rheumatism Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland (I.J.E., R.L.W.); 2Pediatric Endocrinology Section, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland (I.J.E., G.P.C.); 3Department of Pharmacology, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary (E.S.V.); and 4Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, Hungary (E.S.V.)
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In this issue
The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System
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- Article
- Abstract
- I. Introduction
- II. Anatomy and Physiology of the Autonomic Nervous System
- III. Autonomic/Sympathetic Innervation of Lymphoid Organs: Nonsynaptic Communication
- IV. Nonsynaptic Release of Norepinephrine in Lymphoid Organs: Presynaptic Modulation and Effect of Drugs
- V. Systemic and Local Effects of Cytokines on Sympathetic Nervous System Activity
- VI. Expression of Adrenoreceptors on Lymphoid Cells: Signal Transduction
- VII. Role of Sympathetic Innervation in Immune System Development and Hematopoiesis
- VIII. Sympathetic Control of Lymphocyte Traffic and Circulation
- IX. Modulation of Lymphocyte Proliferation and K+Channel Conductance
- X. Modulation of cellular and humoral immunity by catecholamines
- XI. Role of Growth Factors in Sympathetic Nervous System Development and Modulation of the Immune Response
- XII. Physiologic Control of the Sympathetic-Immune Interface: β-Adrenergic Receptor Expression, Coupling, and Desensitization
- XIII. Clinical Implications
- XIV. Pharmacological Manipulation of the Sympathetic-Immune Interface
- XV. Conclusions
- Footnotes
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