Review ArticleReview
Proteinase-Activated Receptors
Scott R. Macfarlane, Michael J. Seatter, Toru Kanke, Gary D. Hunter and Robin Plevin
Pharmacological Reviews June 2001, 53 (2) 245-282;
Scott R. Macfarlane
Department of Physiology and Pharmacology, University of Strathclyde, Strathclyde Institute for Biomedical Sciences, Glasgow, United Kingdom
Michael J. Seatter
Department of Physiology and Pharmacology, University of Strathclyde, Strathclyde Institute for Biomedical Sciences, Glasgow, United Kingdom
Toru Kanke
Department of Physiology and Pharmacology, University of Strathclyde, Strathclyde Institute for Biomedical Sciences, Glasgow, United Kingdom
Gary D. Hunter
Department of Physiology and Pharmacology, University of Strathclyde, Strathclyde Institute for Biomedical Sciences, Glasgow, United Kingdom
Robin Plevin
Department of Physiology and Pharmacology, University of Strathclyde, Strathclyde Institute for Biomedical Sciences, Glasgow, United Kingdom

Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Review ArticleReview
Proteinase-Activated Receptors
Scott R. Macfarlane, Michael J. Seatter, Toru Kanke, Gary D. Hunter and Robin Plevin
Pharmacological Reviews June 1, 2001, 53 (2) 245-282;
Jump to section
- Article
- Abstract
- I. Introduction
- II. Historical Perspectives—Cellular Effects of Thrombin and the Cloning of the Thrombin Receptor, Proteinase-Activated Receptor-1
- III. Pharmacology of Proteinase-Activated Receptor-1
- IV. Functional Responses to Proteinase-Activated Receptor-1 Activation
- V. Proteinase-Activated Receptor-1-Mediated Cellular Signaling
- VI. Desensitization of Proteinase-Activated Receptor-1
- VII. Cloning of Proteinase-Activated Receptor-2
- VIII. Functional Responses to Proteinase-Activated Receptor-2 Activation
- IX. Endogenous Activators of Proteinase-Activated Receptor-2
- X. Pharmacology of Proteinase-Activated Receptor-2
- XI. Proteinase-Activated Receptor-2-Mediated Intracellular Signaling
- XII. Proteinase-Activated Receptor-2 Desensitization
- XIII. Identification and Function of Proteinase-Activated Receptor-3 and Proteinase-Activated Receptor-4
- XIV. Functional and Molecular Interactions Between Proteinase-Activated Receptors
- XV. Proteinase-Activated Receptors as Therapeutic Targets in Disease States
- XVI. Future Perspectives
- Acknowledgments
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement