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History
- Published online December 1, 2001.
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The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Bertil B. Fredholm1,1,
- Adriaan P. IJzerman2,
- Kenneth A. Jacobson3,
- Karl-Norbert Klotz4, and
- Joel Linden5
- 1Department of Physiology and Pharmacology, Section of Molecular Neuropharmacology, Karolinska Institutet, Stockholm, Sweden (B.B.F.); 2Leiden/Amsterdam Center for Drug Research, Gorlaeus Laboratories, Leiden, The Netherlands (A.P.I.); 3Molecular Recognition Section, National Institutes of Health, Bethesda, Maryland (K.A.J.); 4Institut für Pharmakologie und Toxikologie, Universität Würzburg, Würzburg, Germany (K.-N.K.); and 5Department of Physiology, Health Sciences Center, University of Virginia, Charlottesville, Virginia (J.L.)
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- Article
- Abstract
- I. Introduction
- II. Molecular Basis for Receptor Nomenclature
- III. Formation and Levels of the Endogenous Agonist Adenosine
- IV. Structure
- V. Gene Structure
- VI. Binding Sites As Revealed by Site-Directed Mutagenesis
- VII. Distribution
- VIII. Classification of Adenosine Receptors Using Pharmacological Tools
- IX. Signaling
- X. Receptor Regulation
- XI. Assay Systems
- XII. Physiological Roles—Therapeutic Potential
- Footnotes
- Abbreviations
- References
- Figures & Data
- Info & Metrics
- eLetters
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