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Review ArticleReview

International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

A. C. Howlett, F. Barth, T. I. Bonner, G. Cabral, P. Casellas, W. A. Devane, C. C. Felder, M. Herkenham, K. Mackie, B. R. Martin, R. Mechoulam and R. G. Pertwee
Pharmacological Reviews June 2002, 54 (2) 161-202; DOI: https://doi.org/10.1124/pr.54.2.161
A. C. Howlett
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F. Barth
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T. I. Bonner
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G. Cabral
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P. Casellas
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W. A. Devane
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C. C. Felder
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M. Herkenham
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K. Mackie
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B. R. Martin
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R. Mechoulam
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R. G. Pertwee
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Article Information

vol. 54 no. 2 161-202
DOI 
https://doi.org/10.1124/pr.54.2.161
PubMed 
12037135

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online June 1, 2002.

Copyright & Usage 
U.S. Government

Author Information

  1. A. C. Howlett7,
  2. F. Barth1,
  3. T. I. Bonner2,
  4. G. Cabral4,
  5. P. Casellas1,
  6. W. A. Devane5,
  7. C. C. Felder6,
  8. M. Herkenham3,
  9. K. Mackie8,
  10. B. R. Martin5,
  11. R. Mechoulam9, and
  12. R. G. Pertwee10
  1. 1Sanofi-Synthelabo Recherche, Montpellier, Cedex, France (F.B., P.C.); 2Laboratory of Genetics (T.I.B.) and 3Section on Functional Neuroanatomy (M.H.), National Institute of Mental Health, Bethesda, Maryland; Departments of 4Microbiology and Immunology (G.C.) and 5Pharmacology and Toxicology (W.A.D., B.R.M.), Virginia Commonwealth University, Richmond, Virginia; 6Eli Lilly & Co. Ltd., Lilly Research Centre, Windlesham, Surrey, United Kingdom (C.C.F.); 7Neuroscience of Drug Abuse Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University, Durham, North Carolina (A.H.); 8Department of Anesthesiology, University of Washington, Seattle, Washington (K.M.); 9Department of Natural Products, Hebrew University, Medical Faculty, El Kerem Campus, Jerusalem, Israel (R.M.); and 10Department of Biomedical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom (R.G.P.)
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Pharmacological Reviews: 54 (2)
Pharmacological Reviews
Vol. 54, Issue 2
1 Jun 2002
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Review ArticleReview

International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

A. C. Howlett, F. Barth, T. I. Bonner, G. Cabral, P. Casellas, W. A. Devane, C. C. Felder, M. Herkenham, K. Mackie, B. R. Martin, R. Mechoulam and R. G. Pertwee
Pharmacological Reviews June 1, 2002, 54 (2) 161-202; DOI: https://doi.org/10.1124/pr.54.2.161

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Review ArticleReview

International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

A. C. Howlett, F. Barth, T. I. Bonner, G. Cabral, P. Casellas, W. A. Devane, C. C. Felder, M. Herkenham, K. Mackie, B. R. Martin, R. Mechoulam and R. G. Pertwee
Pharmacological Reviews June 1, 2002, 54 (2) 161-202; DOI: https://doi.org/10.1124/pr.54.2.161
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  • Article
    • Abstract
    • I. Introduction: Overview of the Cannabinoid Receptors
    • II. Classification of Ligands That Bind to Cannabinoid Receptors
    • III. Bioassay
    • IV. Cellular Signal Transduction
    • V. Molecular Biology of Cannabinoid Receptors
    • VI. Cannabinoid Receptor Knockout Mice
    • VII. Tissue Distribution of Cannabinoid Receptors
    • VIII. Effects on Neurotransmission
    • IX. Immunological Effects
    • X. Anandamide Is a Vanilloid Receptor Agonist
    • XI. Preliminary Pharmacological Evidence for Non-CB1, Non-CB2 Cannabinoid Receptors
    • XII. Conclusions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
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  • eLetters
  • PDF

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