Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Pharmacological Reviews
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Pharmacological Reviews

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Visit Pharm Rev on Facebook
  • Follow Pharm Rev on Twitter
  • Follow ASPET on LinkedIn
Review ArticleReview

International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels

David E. Clapham, Craig Montell, Guenter Schultz and David Julius
Pharmacological Reviews December 2003, 55 (4) 591-596; DOI: https://doi.org/10.1124/pr.55.4.6
David E. Clapham
Howard Hughes Medical Institute, Children's Hospital, Boston, Massachusetts (D.E.C.); Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, Maryland C.M.); Pharmakologisches Institut, Freie Universitaet Berlin, Berlin, Germany (G.S.); and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California (D.J.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Craig Montell
Howard Hughes Medical Institute, Children's Hospital, Boston, Massachusetts (D.E.C.); Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, Maryland C.M.); Pharmakologisches Institut, Freie Universitaet Berlin, Berlin, Germany (G.S.); and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California (D.J.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Guenter Schultz
Howard Hughes Medical Institute, Children's Hospital, Boston, Massachusetts (D.E.C.); Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, Maryland C.M.); Pharmakologisches Institut, Freie Universitaet Berlin, Berlin, Germany (G.S.); and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California (D.J.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David Julius
Howard Hughes Medical Institute, Children's Hospital, Boston, Massachusetts (D.E.C.); Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, Maryland C.M.); Pharmakologisches Institut, Freie Universitaet Berlin, Berlin, Germany (G.S.); and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California (D.J.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Abstract

The transient receptor potential (TRP) proteins are six transmembrane-containing subunits that combine to form cation-selective ion channels. TRP channels are present in yeast, Drosophila, Caenorhabditis elegans, and mammals. They are widely distributed and sense local changes in stimuli ranging from light to temperature and osmolarity. Mammals contain at least 22 distinct genes encoding these ion channels. This summary article presents an overview of the molecular relationships among the TRP channels and a standard nomenclature for them, which is derived from the IUPHAR Compendium of Voltage-Gated Ion Channels.1 The complete Compendium, including data tables for each member of the TRP channel family, can be found at http://www.iuphar-db.org/iuphar-ic/.

  • The American Society for Pharmacology and Experimental Therapeutics
View Full Text
PreviousNext
Back to top

In this issue

Pharmacological Reviews: 55 (4)
Pharmacological Reviews
Vol. 55, Issue 4
1 Dec 2003
  • Table of Contents
  • About the Cover
  • Index by author
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Pharmacological Reviews article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels
(Your Name) has forwarded a page to you from Pharmacological Reviews
(Your Name) thought you would be interested in this article in Pharmacological Reviews.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Review ArticleReview

International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels

David E. Clapham, Craig Montell, Guenter Schultz and David Julius
Pharmacological Reviews December 1, 2003, 55 (4) 591-596; DOI: https://doi.org/10.1124/pr.55.4.6

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Review ArticleReview

International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels

David E. Clapham, Craig Montell, Guenter Schultz and David Julius
Pharmacological Reviews December 1, 2003, 55 (4) 591-596; DOI: https://doi.org/10.1124/pr.55.4.6
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Structural Features
    • TRP Channel Functional Features
    • TRPC (Short, Canonical TRPC) Family
    • TRPV (osm-9-Like or Vanilloid Receptor TRP) Family
    • TRPM (Long TRPC, Melastatin) Family
    • TRPA Ankyrin-Repeat TRP Channel Family
    • Conclusion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology
  • G Protein Modulation of Voltage-Gated Calcium Channels
Show more Reviews

Similar Articles

  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Pharmacological Reviews
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacology Research & Perspectives
ISSN 1521-0081 (Online)

Copyright © 2021 by the American Society for Pharmacology and Experimental Therapeutics