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History
- Published online March 4, 2004.
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The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Anna Catania,
- Stefano Gatti,
- Gualtiero Colombo, and
- James M. Lipton
- Divisions of Internal Medicine (A.C., G.C.) and Liver Transplantation (S.G.), Ospedale Maggiore di Milano, Istituto di Ricovero e Cura a Carattere Scientifico, Milano, Italy; and Zengen, Inc. (J.M.L.), Woodland Hills, California
- Address correspondence to: Dr. Anna Catania, Divisione di Medicina Interna I, Pad. Granelli, Ospedale Maggiore di Milano IRCCS, Via F. Sforza 35, Milano 20122, Italy. E-mail: anna.catania{at}unimi.it
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- Article
- Abstract
- I. Introduction
- II. Proopiomelanocortin Gene, Gene Expression, and Post-Translational Processing
- III. Melanocortin Receptors and Their Endogenous Antagonists
- IV. Intracellular Signaling
- V. Structure-Activity Relationship of Melanocortin Peptides
- VI. Mechanism of the Anti-Inflammatory Action of Melanocortins
- VII. Antipyretic Influences of Melanocortins
- VIII. Changes in Endogenous α-Melanocyte-Stimulating Hormone in Inflammatory Disorders
- IX. Potential Therapeutic Targets Based on Preclinical Studies in Inflammatory Disorders
- X. Advantages over Currently Used Anti-Inflammatory Drugs and Potential Disadvantages
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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