Metabolism and Disposition Kinetics of Nicotine

Division of Clinical Pharmacology and Experimental Therapeutics, Medical Service, San Francisco General Hospital Medical Center, and the Departments of Medicine and Psychiatry, University of California, San Francisco, California

Address correspondence to: Dr. Neal L. Benowitz, Division of Clinical Pharmacology and Experimental Therapeutics, University of California, San Francisco, Box 1220, San Francisco, CA 94143-1220. E-mail: nbeno{at}itsa.ucsf.edu

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	Abstract	Full	Pdf
Feb 2005	120	58	99
Mar 2005	266	679	352
Apr 2005	152	565	196
May 2005	155	422	160
Jun 2005	110	333	143
Jul 2005	99	315	111
Aug 2005	92	296	139
Sep 2005	111	339	119
Oct 2005	153	351	122
Nov 2005	148	255	92
Dec 2005	120	215	85
Jan 2006	170	88	80
Feb 2006	125	81	79
Mar 2006	82	403	222
Apr 2006	68	224	160
May 2006	95	284	188
Jun 2006	72	207	142
Jul 2006	67	174	121
Aug 2006	75	288	173
Sep 2006	91	263	175
Oct 2006	128	274	177
Nov 2006	128	358	174
Dec 2006	92	191	121
Jan 2007	99	221	375
Feb 2007	140	196	135
Mar 2007	144	252	207
Apr 2007	131	275	181
May 2007	105	238	182
Jun 2007	98	180	168
Jul 2007	119	233	165
Aug 2007	106	204	149
Sep 2007	104	161	144
Oct 2007	108	225	178
Nov 2007	80	229	148
Dec 2007	78	172	100
Jan 2008	102	317	158
Feb 2008	88	267	143
Mar 2008	99	286	131
Apr 2008	118	257	157
May 2008	150	251	178
Jun 2008	130	255	144
Jul 2008	144	279	154
Aug 2008	185	229	98
Sep 2008	150	169	121
Oct 2008	140	240	151
Nov 2008	189	238	148
Dec 2008	118	207	399
Jan 2009	113	201	147
Feb 2009	124	192	123
Mar 2009	141	242	161
Apr 2009	114	311	127
May 2009	141	264	153
Jun 2009	108	258	123
Jul 2009	137	222	130
Aug 2009	109	235	136
Sep 2009	126	174	137
Oct 2009	176	217	170
Nov 2009	132	230	112
Dec 2009	147	151	102
Jan 2010	187	150	144
Feb 2010	262	135	165
Mar 2010	335	356	186
Apr 2010	169	175	103
May 2010	169	146	105
Jun 2010	163	156	109
Jul 2010	135	154	80
Aug 2010	153	216	109
Sep 2010	134	328	126
Oct 2010	193	332	133
Nov 2010	195	264	139
Dec 2010	156	283	127
Jan 2011	200	248	128
Feb 2011	214	256	127
Mar 2011	246	302	160
Apr 2011	182	301	159
May 2011	224	226	145
Jun 2011	201	231	158
Jul 2011	181	259	123
Aug 2011	196	338	146
Sep 2011	212	466	149
Oct 2011	294	552	215
Nov 2011	241	634	204
Dec 2011	195	572	187
Jan 2012	203	613	193
Feb 2012	205	754	215
Mar 2012	269	787	214
Apr 2012	178	711	190
May 2012	193	771	167
Jun 2012	126	701	150
Jul 2012	159	827	158
Aug 2012	132	864	171
Sep 2012	133	1055	231
Oct 2012	192	1606	285
Nov 2012	150	1034	235
Dec 2012	148	1119	175
Jan 2013	183	1147	201
Feb 2013	136	1157	166
Mar 2013	181	919	184
Apr 2013	260	878	238
May 2013	185	706	162
Jun 2013	87	675	124
Jul 2013	117	862	168
Aug 2013	114	901	134
Sep 2013	259	1788	178
Oct 2013	507	4165	281
Nov 2013	411	1865	237
Dec 2013	144	1330	173
Jan 2014	129	1419	178
Feb 2014	193	2071	229
Mar 2014	219	1746	246
Apr 2014	186	1731	211
May 2014	142	1791	198
Jun 2014	117	1228	156
Jul 2014	159	1429	145
Aug 2014	109	1314	135
Sep 2014	131	1093	175
Oct 2014	156	1356	193
Nov 2014	163	1395	196
Dec 2014	110	1100	153
Jan 2015	131	1235	190
Feb 2015	132	1008	206
Mar 2015	116	1319	146
Apr 2015	144	1380	154
May 2015	290	1314	295
Jun 2015	172	1066	194
Jul 2015	139	905	132
Aug 2015	109	864	137
Sep 2015	174	902	134
Oct 2015	472	1311	206
Nov 2015	467	1397	196
Dec 2015	273	1101	110
Jan 2016	165	1208	123
Feb 2016	134	1166	155
Mar 2016	178	1140	167
Apr 2016	123	996	157
May 2016	188	895	142
Jun 2016	161	950	101
Jul 2016	149	1071	120
Aug 2016	166	990	113
Sep 2016	86	1114	117
Oct 2016	40	1072	114
Nov 2016	34	563	111
Dec 2016	31	718	118
Jan 2017	40	696	101
Feb 2017	39	554	115
Mar 2017	46	748	114
Apr 2017	29	572	160
May 2017	42	557	127
Jun 2017	35	508	94
Jul 2017	27	527	75
Aug 2017	28	505	114
Sep 2017	34	1900	153
Oct 2017	48	2290	116
Nov 2017	50	702	118
Dec 2017	43	673	75
Jan 2018	39	458	112
Feb 2018	66	539	104
Mar 2018	45	583	134
Apr 2018	42	1041	143
May 2018	37	457	138
Jun 2018	26	350	96
Jul 2018	20	435	123
Aug 2018	32	328	121
Sep 2018	29	455	128
Oct 2018	33	500	133
Nov 2018	32	803	120
Dec 2018	641	178	70
Jan 2019	868	50	45
Feb 2019	797	62	36
Mar 2019	480	63	36
Apr 2019	518	70	60
May 2019	439	73	44
Jun 2019	299	62	31
Jul 2019	321	43	35
Aug 2019	286	29	20
Sep 2019	397	82	41
Oct 2019	515	94	40
Nov 2019	418	66	38
Dec 2019	310	35	19
Jan 2020	298	41	17
Feb 2020	447	53	21
Mar 2020	491	42	28
Apr 2020	370	38	16
May 2020	458	26	18
Jun 2020	279	39	21
Jul 2020	245	23	12
Aug 2020	203	19	9
Sep 2020	284	37	21
Oct 2020	392	57	18
Nov 2020	448	43	34
Dec 2020	316	43	22
Jan 2021	290	41	27
Feb 2021	246	45	19
Mar 2021	432	42	21
Apr 2021	375	55	15
May 2021	299	38	19
Jun 2021	291	37	15
Jul 2021	293	31	20
Aug 2021	226	45	14
Sep 2021	248	65	28
Oct 2021	236	18	13