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History
- Published online September 12, 2006.
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The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Ting-Chao Chou
- Preclinical Pharmacology Core Laboratory, Molecular Pharmacology and Chemistry Program, Memorial Sloan-Kettering Cancer Center, New York, New York
- Address correspondence to: Dr. Ting-Chao Chou, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021. E-mail: chout{at}mskcc.org
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Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
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- Article
- Abstract
- I. Introduction
- II. Theoretical Basis for Dose-Effect Analysis
- III. Experimental Design for Drug Combinations
- IV. Computerized Automation, Graphic Simulation, and Informatics
- V. Selected Examples of Cited Applications
- VI. Illustrations of Real Data Analysis with Mass-Action Law-Based Computer Software
- Appendix I: Derivation of the Multiple Drug-Effect Equation
- Glossary
- Acknowledgments
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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