Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)

Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)

Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)

Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)

Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)

Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)

Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)

Laboratoire de Biologie Moléculaire et Cellulaire de l'Ecole Normale Supérieure de Lyon, Unité Mixte de Recherche, Centre National de la Recherche Scientifique 5665, Laboratoire Associé Institut National de la Recherche Agronomique 913, l'Institut Fédératif de Recherches 128, Lyon, France (F.F., J.S.); Diabetes Center and Department of Medicine (J.D.B.), and Program in Chemistry and Chemical Biology, Department of Pharmaceutical Chemistry (T.S.S.), University of California, San Francisco, San Francisco, California; Clinical Endocrinology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland (D.F.); Departments of Medicine Pediatrics, The University of Chicago, Chicago, Illinois (S.R.); Departments of Pharmacology and Medicine, New York University School of Medicine, New York, New York (H.S.); and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden (B.V.)