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Pharmacological Reviews

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Cover Caption

About the cover: The UPS. Ubiquitin (Ub) is activated in an ATP-dependent reaction by the E1 ubiquitin-activating enzyme and appended to target proteins by the successive action of E2 ubiquitin-conjugating enzymes, E3 ubiquitin ligases, and E4 chain elongation factors. See the article by Yi and Ehlers on page 14 of this issue.

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Pharmacological Reviews: 59 (1)
Pharmacological Reviews
Vol. 59, Issue 1
1 Mar 2007
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  • Nitric oxide: physiology, pathophysiology, and pharmacology.
  • The Glutamate Receptor Ion Channels
  • Receptors for Purines and Pyrimidines
  • Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitization and Signaling
  • Glutamate Receptor Ion Channels: Structure, Regulation, and Function
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