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Review ArticleReview Article

The Endomorphin System and Its Evolving Neurophysiological Role

Jakub Fichna, Anna Janecka, Jean Costentin and Jean-Claude Do Rego
Pharmacological Reviews March 2007, 59 (1) 88-123; DOI: https://doi.org/10.1124/pr.59.1.3
Jakub Fichna
Laboratory of Experimental Neuropsychopharmacology, Centre National de la Recherche Scientifique-Formation de Recherche en Evolution 2735, European Institute of Peptide Research (Institut Fédératif de Recherches Multidisciplinaires sur les Peptides 23), Faculty of Medicine and Pharmacy, Institute of Biomedical Research, University of Rouen, Rouen, France (J.F., J.C., J.-C.d.R.); and Laboratory of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland (J.F., A.J.)
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Anna Janecka
Laboratory of Experimental Neuropsychopharmacology, Centre National de la Recherche Scientifique-Formation de Recherche en Evolution 2735, European Institute of Peptide Research (Institut Fédératif de Recherches Multidisciplinaires sur les Peptides 23), Faculty of Medicine and Pharmacy, Institute of Biomedical Research, University of Rouen, Rouen, France (J.F., J.C., J.-C.d.R.); and Laboratory of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland (J.F., A.J.)
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Jean Costentin
Laboratory of Experimental Neuropsychopharmacology, Centre National de la Recherche Scientifique-Formation de Recherche en Evolution 2735, European Institute of Peptide Research (Institut Fédératif de Recherches Multidisciplinaires sur les Peptides 23), Faculty of Medicine and Pharmacy, Institute of Biomedical Research, University of Rouen, Rouen, France (J.F., J.C., J.-C.d.R.); and Laboratory of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland (J.F., A.J.)
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Jean-Claude Do Rego
Laboratory of Experimental Neuropsychopharmacology, Centre National de la Recherche Scientifique-Formation de Recherche en Evolution 2735, European Institute of Peptide Research (Institut Fédératif de Recherches Multidisciplinaires sur les Peptides 23), Faculty of Medicine and Pharmacy, Institute of Biomedical Research, University of Rouen, Rouen, France (J.F., J.C., J.-C.d.R.); and Laboratory of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland (J.F., A.J.)
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Article Information

vol. 59 no. 1 88-123
DOI 
https://doi.org/10.1124/pr.59.1.3
PubMed 
17329549

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online February 28, 2007.

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jakub Fichna,
  2. Anna Janecka,
  3. Jean Costentin, and
  4. Jean-Claude Do Rego
  1. Laboratory of Experimental Neuropsychopharmacology, Centre National de la Recherche Scientifique-Formation de Recherche en Evolution 2735, European Institute of Peptide Research (Institut Fédératif de Recherches Multidisciplinaires sur les Peptides 23), Faculty of Medicine and Pharmacy, Institute of Biomedical Research, University of Rouen, Rouen, France (J.F., J.C., J.-C.d.R.); and Laboratory of Biomolecular Chemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland (J.F., A.J.)
  1. Address correspondence to: Dr. Jean-Claude do Rego, Laboratory of Experimental Neuropsychopharmacology, CNRS FRE 2735, IFRMP 23, Faculty of Medicine & Pharmacy, University of Rouen, 22, Boulevard Gambetta, 76183 Rouen cedex, France. E-mail: jean-claude.dorego{at}univ-rouen.fr
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Pharmacological Reviews: 59 (1)
Pharmacological Reviews
Vol. 59, Issue 1
1 Mar 2007
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Review ArticleReview Article

The Endomorphin System and Its Evolving Neurophysiological Role

Jakub Fichna, Anna Janecka, Jean Costentin and Jean-Claude Do Rego
Pharmacological Reviews March 1, 2007, 59 (1) 88-123; DOI: https://doi.org/10.1124/pr.59.1.3

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Review ArticleReview Article

The Endomorphin System and Its Evolving Neurophysiological Role

Jakub Fichna, Anna Janecka, Jean Costentin and Jean-Claude Do Rego
Pharmacological Reviews March 1, 2007, 59 (1) 88-123; DOI: https://doi.org/10.1124/pr.59.1.3
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  • Article
    • Abstract
    • I. Introduction
    • II. Structure-Activity Relationship Studies
    • III. Distribution
    • IV. Receptors
    • V. Enzymatic Degradation
    • VI. Neurophysiological Role
    • VII. Conclusions
    • Acknowledgments
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