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Review ArticleReview Article

Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy

David S. Miller, Björn Bauer and Anika M. S. Hartz
Pharmacological Reviews June 2008, 60 (2) 196-209; DOI: https://doi.org/10.1124/pr.107.07109
David S. Miller
Laboratory of Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina (D.S.M., B.B., A.M.S.H.); and College of Pharmacy (B.B.) and Medical School (A.M.S.H.), University of Minnesota, Duluth, Minnesota
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Björn Bauer
Laboratory of Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina (D.S.M., B.B., A.M.S.H.); and College of Pharmacy (B.B.) and Medical School (A.M.S.H.), University of Minnesota, Duluth, Minnesota
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Anika M. S. Hartz
Laboratory of Pharmacology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina (D.S.M., B.B., A.M.S.H.); and College of Pharmacy (B.B.) and Medical School (A.M.S.H.), University of Minnesota, Duluth, Minnesota
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Pharmacological Reviews: 60 (2)
Pharmacological Reviews
Vol. 60, Issue 2
1 Jun 2008
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Review ArticleReview Article

Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy

David S. Miller, Björn Bauer and Anika M. S. Hartz
Pharmacological Reviews June 1, 2008, 60 (2) 196-209; DOI: https://doi.org/10.1124/pr.107.07109

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Review ArticleReview Article

Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy

David S. Miller, Björn Bauer and Anika M. S. Hartz
Pharmacological Reviews June 1, 2008, 60 (2) 196-209; DOI: https://doi.org/10.1124/pr.107.07109
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  • Article
    • Abstract
    • I. Introduction
    • II. The Blood-Brain Barrier
    • III. P-glycoprotein, a Critical Element of the Selective/Biochemical Barrier
    • IV. Modulation of P-Glycoprotein Transport Activity
    • V. Perspectives
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