Review ArticleReview Article
Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection
Steven D. Buckingham, Andrew K. Jones, Laurence A. Brown and David B. Sattelle
Pharmacological Reviews March 2009, 61 (1) 39-61; DOI: https://doi.org/10.1124/pr.108.000562
Steven D. Buckingham
Medical Research Council Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
Andrew K. Jones
Medical Research Council Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
Laurence A. Brown
Medical Research Council Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
David B. Sattelle
Medical Research Council Functional Genomics Unit, Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
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In this issue
Review ArticleReview Article
Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection
Steven D. Buckingham, Andrew K. Jones, Laurence A. Brown and David B. Sattelle
Pharmacological Reviews March 1, 2009, 61 (1) 39-61; DOI: https://doi.org/10.1124/pr.108.000562
Review ArticleReview Article
Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection
Steven D. Buckingham, Andrew K. Jones, Laurence A. Brown and David B. Sattelle
Pharmacological Reviews March 1, 2009, 61 (1) 39-61; DOI: https://doi.org/10.1124/pr.108.000562
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- Article
- Abstract
- I. Introduction
- II. β-Amyloid: Biophysics and Roles in Alzheimer's Disease
- III. Nicotinic Acetylcholine Receptors: Structure, Function and Roles in Neuroprotection
- IV. β-Amyloid Peptide Toxicity: Is It Mediated in Part through Nicotinic Acetylcholine Receptors?
- V. Loss of Cholinergic Neurons and Nicotinic Acetylcholine Receptors in Alzheimer's Disease
- VI. Nicotinic Acetylcholine Receptors: Molecular Switches Controlling Survival or Death
- VII. Future Directions
- VIII. Conclusion
- Acknowledgments
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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