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Review ArticleReview Article

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

Curtis D. Klaassen and Lauren M. Aleksunes
Pharmacological Reviews March 2010, 62 (1) 1-96; DOI: https://doi.org/10.1124/pr.109.002014
Curtis D. Klaassen
Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas
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Lauren M. Aleksunes
Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas
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Article Information

vol. 62 no. 1 1-96
DOI 
https://doi.org/10.1124/pr.109.002014
PubMed 
20103563

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online February 17, 2010.

Article Versions

  • Earlier version (January 26, 2010 - 06:33).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Curtis D. Klaassen and
  2. Lauren M. Aleksunes1
  1. Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas
  1. Address correspondence to:
    Dr. Curtis Klaassen, Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160-7417. E-mail: cklaasse{at}kumc.edu
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Pharmacological Reviews: 62 (1)
Pharmacological Reviews
Vol. 62, Issue 1
1 Mar 2010
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Review ArticleReview Article

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

Curtis D. Klaassen and Lauren M. Aleksunes
Pharmacological Reviews March 1, 2010, 62 (1) 1-96; DOI: https://doi.org/10.1124/pr.109.002014

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Review ArticleReview Article

Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation

Curtis D. Klaassen and Lauren M. Aleksunes
Pharmacological Reviews March 1, 2010, 62 (1) 1-96; DOI: https://doi.org/10.1124/pr.109.002014
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  • Article
    • Abstract
    • I. Introduction
    • II. Transporter Families: Tissue Distribution, Subcellular Localization, and Substrates
    • III. Transporter Function in Various Tissues
    • IV. Post-Translational Regulation and Subcellular Trafficking of Transporters
    • V. Sex Differences in Transporter Expression
    • VI. Ontogeny of Transporters
    • VII. Regulation of Hepatic Transporters by Xenobiotic-Activated Transcription Factors
    • VIII. Regulation of Hepatic Transporters in Pathophysiological Conditions
    • IX. Future Directions
    • Acknowledgments.
    • Footnotes
    • References
  • Figures & Data
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