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Review ArticleReview Article

Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines

Glenda E. Gillies and Simon McArthur
Pharmacological Reviews June 2010, 62 (2) 155-198; DOI: https://doi.org/10.1124/pr.109.002071
Glenda E. Gillies
Division of Experimental Medicine, Hammersmith Hospital Campus, Imperial College, London, United Kingdom
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Simon McArthur
Division of Experimental Medicine, Hammersmith Hospital Campus, Imperial College, London, United Kingdom
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Article Information

vol. 62 no. 2 155-198
DOI 
https://doi.org/10.1124/pr.109.002071
PubMed 
20392807

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online May 14, 2010.

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  • Earlier version (April 14, 2010 - 05:14).
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Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Glenda E. Gillies and
  2. Simon McArthur
  1. Division of Experimental Medicine, Hammersmith Hospital Campus, Imperial College, London, United Kingdom
  1. Address correspondence to: Dr. Glenda E. Gillies, Centre for Neuroscience, Department of Medicine, Hammersmith Hospital, Imperial College Faculty of Medicine, DuCane Road, London W12 ONN, UK. E-mail: g.gillies{at}imperial.ac.uk
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Pharmacological Reviews: 62 (2)
Pharmacological Reviews
Vol. 62, Issue 2
1 Jun 2010
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Review ArticleReview Article

Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines

Glenda E. Gillies and Simon McArthur
Pharmacological Reviews June 1, 2010, 62 (2) 155-198; DOI: https://doi.org/10.1124/pr.109.002071

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Review ArticleReview Article

Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines

Glenda E. Gillies and Simon McArthur
Pharmacological Reviews June 1, 2010, 62 (2) 155-198; DOI: https://doi.org/10.1124/pr.109.002071
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  • Article
    • Abstract
    • I. Introduction
    • II. Definitions, Concepts, and Why Brain Sex Dimorphisms Are Important
    • III. Estrogen Synthesis and Signaling Mechanisms
    • IV. Lessons from the Hypothalamus
    • V. Parkinson's Disease and Sex Dimorphisms in the Nigrostriatal Dopaminergic Pathway
    • VI. Sex, Estrogens, and Drug Abuse
    • VII. Learning, Memory, and Alzheimer's Disease
    • VIII. Sex Dimorphisms in the Stress Response
    • VIII. Summary and the Way Forward
    • Acknowledgments.
    • Footnotes
    • References
  • Figures & Data
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