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Research ArticleIUPHAR Nomenclature Reports

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

Margarita L. Dubocovich, Philippe Delagrange, Diana N. Krause, David Sugden, Daniel P. Cardinali and James Olcese
Pharmacological Reviews September 2010, 62 (3) 343-380; DOI: https://doi.org/10.1124/pr.110.002832
Margarita L. Dubocovich
Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York (M.L.D.); Department Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois (M.L.D.); Experimental Sciences Department, Institut de Recherches Servier, Suresnes, France (P.D.); Department of Pharmacology, College of Medicine, University of California, Irvine, California (D.N.K.); Division of Reproduction and Endocrinology, School of Biomedical and Health Sciences, King's College London, United Kingdom (D.S.); Department of Teaching & Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, Argentina (D.P.C.); and Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida (J.O.)
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Philippe Delagrange
Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York (M.L.D.); Department Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois (M.L.D.); Experimental Sciences Department, Institut de Recherches Servier, Suresnes, France (P.D.); Department of Pharmacology, College of Medicine, University of California, Irvine, California (D.N.K.); Division of Reproduction and Endocrinology, School of Biomedical and Health Sciences, King's College London, United Kingdom (D.S.); Department of Teaching & Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, Argentina (D.P.C.); and Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida (J.O.)
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Diana N. Krause
Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York (M.L.D.); Department Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois (M.L.D.); Experimental Sciences Department, Institut de Recherches Servier, Suresnes, France (P.D.); Department of Pharmacology, College of Medicine, University of California, Irvine, California (D.N.K.); Division of Reproduction and Endocrinology, School of Biomedical and Health Sciences, King's College London, United Kingdom (D.S.); Department of Teaching & Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, Argentina (D.P.C.); and Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida (J.O.)
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David Sugden
Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York (M.L.D.); Department Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois (M.L.D.); Experimental Sciences Department, Institut de Recherches Servier, Suresnes, France (P.D.); Department of Pharmacology, College of Medicine, University of California, Irvine, California (D.N.K.); Division of Reproduction and Endocrinology, School of Biomedical and Health Sciences, King's College London, United Kingdom (D.S.); Department of Teaching & Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, Argentina (D.P.C.); and Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida (J.O.)
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Daniel P. Cardinali
Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York (M.L.D.); Department Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois (M.L.D.); Experimental Sciences Department, Institut de Recherches Servier, Suresnes, France (P.D.); Department of Pharmacology, College of Medicine, University of California, Irvine, California (D.N.K.); Division of Reproduction and Endocrinology, School of Biomedical and Health Sciences, King's College London, United Kingdom (D.S.); Department of Teaching & Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, Argentina (D.P.C.); and Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida (J.O.)
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James Olcese
Department of Pharmacology and Toxicology, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York (M.L.D.); Department Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois (M.L.D.); Experimental Sciences Department, Institut de Recherches Servier, Suresnes, France (P.D.); Department of Pharmacology, College of Medicine, University of California, Irvine, California (D.N.K.); Division of Reproduction and Endocrinology, School of Biomedical and Health Sciences, King's College London, United Kingdom (D.S.); Department of Teaching & Research, Faculty of Medical Sciences, Pontificia Universidad Católica Argentina, Buenos Aires, Argentina (D.P.C.); and Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, Florida (J.O.)
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Pharmacological Reviews: 62 (3)
Pharmacological Reviews
Vol. 62, Issue 3
1 Sep 2010
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Research ArticleIUPHAR Nomenclature Reports

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

Margarita L. Dubocovich, Philippe Delagrange, Diana N. Krause, David Sugden, Daniel P. Cardinali and James Olcese
Pharmacological Reviews September 1, 2010, 62 (3) 343-380; DOI: https://doi.org/10.1124/pr.110.002832

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Research ArticleIUPHAR Nomenclature Reports

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

Margarita L. Dubocovich, Philippe Delagrange, Diana N. Krause, David Sugden, Daniel P. Cardinali and James Olcese
Pharmacological Reviews September 1, 2010, 62 (3) 343-380; DOI: https://doi.org/10.1124/pr.110.002832
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  • Article
    • Abstract
    • I. Introduction
    • II. G Protein-Coupled Melatonin Receptor Family
    • III. Cellular Signaling of MT1 and MT2 Melatonin Receptors
    • IV. MT1 and MT2 Melatonin Receptors: Structure-Activity Relationships and Selective Ligands
    • V. MT1- and MT2-Mediated Functional Responses
    • VI. Melatonin receptors as therapeutic targets
    • VII. Conclusion
    • Acknowledgments.
    • Footnotes
    • References
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