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History
- Published online August 17, 2010.
Copyright & Usage
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Murielle Mimeault and
- Surinder K. Batra
- David Sibley, ASSOCIATE EDITOR
- Address correspondence to: Dr. Surinder K. Batra, Department of Biochemistry and Molecular Biology, Eppley Institute for Research in Cancer, and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198-5870. E-mail: sbatra{at}unmc.edu
Funding
National Institutes of Health
CA78590; CA111294; CA131944; CA133774; CA138791
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- Article
- Abstract
- I. Introduction
- II. The Hedgehog Signal Transduction Pathway and Regulatory Mechanisms
- III. Critical Functions of the Hedgehog Signaling Pathway during Embryonic and Postnatal Development and Adult Life and Their Therapeutic Implications
- IV. Critical Functions of the Hedgehog Signaling Pathway in the Malignant Transformation of Cancer- and Metastasis-Initiating Cells and Their Progenies
- V. Targeted Therapies
- VI. Conclusions and Future Directions
- Acknowledgments.
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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