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Research ArticleIUPHAR Nomenclature Reports

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

Jerold Chun, Timothy Hla, Kevin R. Lynch, Sarah Spiegel and Wouter H. Moolenaar
Pharmacological Reviews December 2010, 62 (4) 579-587; DOI: https://doi.org/10.1124/pr.110.003111
Jerold Chun
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Timothy Hla
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Kevin R. Lynch
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Sarah Spiegel
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Wouter H. Moolenaar
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    TABLE 1

    Lysophospholipid receptor names, gene names, and size based on amino acid number and molecular mass

    Gene names for LPA6 are currently provisional.

    Receptor NameGene Name (Historical Aliases)Predicted No. of Amino AcidsPredicted Molecular Mass
    HumanMouseHumanMouse
    kDa
    LPA1LPAR1Lpar136436441.0
    (EDG2; VZG1; LPA1, GPR26; edg-2; vzg-1; Gpcr26; Mrec1.3; rec0.1.3)(Edg2; Kdt2; lpA1; vzg-1; Gpcr26; AI326300; MGC29102; 5031439C20)
    LPA2LPAR2Lpar235134838.9
    (EDG4; EDG-4; LPA2, LPA-2; FLJ93869)(Edg4; lpA2)
    LPA3LPAR3Lpar335335440.0
    (EDG7; Edg-7; LPA3; HOFNH30; FLJ98231; RP4-678I3)(Edg7; lpA3)
    LPA4LPAR4Lpar437037041.8
    (P2Y9; GPR23; P2RY9; P2Y5-LIKE)(p2y9; Gpr23; 5730485F04Rik)
    LPA5LPAR5Lpar537238441–43
    (GPR92; GPR93; KPG_010)(GPR93; Gpr92; Gm1072)
    LPA6LPAR6 (proposed)Lpar6 (proposed)34434439.3
    (LAH3; P2Y5; P2RY5; MGC120358)(P2y5; P2ry5; 2610302I02Rik)
    S1P1S1PR1S1pr138238242.8
    (EDG1; EDG-1; LPB1, ECGF1; CHEDG1; D1S3362; FLJ58121)(Edg1; lpB1; S1p1; AI849002)
    S1P2S1PR2S1pr235335238.8
    (EDG5; H218; LPB2; AGR16; EDG-5; Gpcr13)Edg5; H218; lpB2; S1p2; Gpcr13; 1100001A16Rik;
    S1P3S1PR3S1pr337837842.3
    (EDG3; LPB3; EDG-3; FLJ37523; FLJ93220; MGC71696)(Edg3; lpB3; S1p3; AI132464)
    S1P4S1PR4S1pr438438641.6
    (EDG6; LPC1; SLP4)(Edg6; lpC1; S1p4; MGC129298)
    S1P5S1PR5S1pr539840041.8
    (EDG8; Edg-8; LPB4, SPPR-1; SPPR-2)(Edg8; S1p5; lpB4)
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Pharmacological Reviews: 62 (4)
Pharmacological Reviews
Vol. 62, Issue 4
1 Dec 2010
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Research ArticleIUPHAR Nomenclature Reports

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

Jerold Chun, Timothy Hla, Kevin R. Lynch, Sarah Spiegel and Wouter H. Moolenaar
Pharmacological Reviews December 1, 2010, 62 (4) 579-587; DOI: https://doi.org/10.1124/pr.110.003111

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Research ArticleIUPHAR Nomenclature Reports

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

Jerold Chun, Timothy Hla, Kevin R. Lynch, Sarah Spiegel and Wouter H. Moolenaar
Pharmacological Reviews December 1, 2010, 62 (4) 579-587; DOI: https://doi.org/10.1124/pr.110.003111
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  • Article
    • Abstract
    • I. Introduction
    • II. Lysophospholipid Receptor Nomenclature
    • III. Lysophospholipid Receptor Agonists/Antagonists
    • V. Conclusions
    • Acknowledgments.
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