Review ArticleReview Article
NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair
Fan Jiang, Yun Zhang and Gregory J. Dusting
David R. Sibley, ASSOCIATE EDITOR
Pharmacological Reviews March 2011, 63 (1) 218-242; DOI: https://doi.org/10.1124/pr.110.002980
Fan Jiang
Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, Shandong Province, China (F.J., Y.Z.); and O'Brien Institute (G.J.D.) and Department of Surgery (F.J., G.J.D.), University of Melbourne, Melbourne, Victoria, Australia
Yun Zhang
Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, Shandong Province, China (F.J., Y.Z.); and O'Brien Institute (G.J.D.) and Department of Surgery (F.J., G.J.D.), University of Melbourne, Melbourne, Victoria, Australia
Gregory J. Dusting
Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, Shandong Province, China (F.J., Y.Z.); and O'Brien Institute (G.J.D.) and Department of Surgery (F.J., G.J.D.), University of Melbourne, Melbourne, Victoria, Australia
David R. Sibley
Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Health, Qilu Hospital, Shandong University, Jinan, Shandong Province, China (F.J., Y.Z.); and O'Brien Institute (G.J.D.) and Department of Surgery (F.J., G.J.D.), University of Melbourne, Melbourne, Victoria, Australia
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Review ArticleReview Article
NADPH Oxidase-Mediated Redox Signaling: Roles in Cellular Stress Response, Stress Tolerance, and Tissue Repair
Fan Jiang, Yun Zhang and Gregory J. Dusting
Pharmacological Reviews March 1, 2011, 63 (1) 218-242; DOI: https://doi.org/10.1124/pr.110.002980
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- Article
- Abstract
- I. Introduction
- II. NADPH Oxidase Is Activated by Various Cellular Stresses
- III. Signal Output from NADPH Oxidase
- IV. Cell Survival versus Apoptosis
- V. Mechanisms of NADPH Oxidase Activation
- VI. NADPH Oxidase and the Stress Response Signaling Paradigm
- VII. NADPH Oxidase and Tissue Regeneration
- VIII. Role of NADPH Oxidase-Mediated Stress Response in Vivo
- IX. Concluding Remarks—NADPH Oxidase at the Crossroads
- Authorship Contributions
- Acknowledgments
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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