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Review ArticleReview Article

Neuropharmacology of the Naturally Occurring κ-Opioid Hallucinogen Salvinorin A

Christopher W. Cunningham, Richard B. Rothman and Thomas E. Prisinzano
Eric L. Barker, ASSOCIATE EDITOR
Pharmacological Reviews June 2011, 63 (2) 316-347; DOI: https://doi.org/10.1124/pr.110.003244
Christopher W. Cunningham
Department of Medicinal Chemistry, the University of Kansas, Lawrence, Kansas (C.W.C., T.E.P.); and Clinical Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland (R.B.R.)
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Richard B. Rothman
Department of Medicinal Chemistry, the University of Kansas, Lawrence, Kansas (C.W.C., T.E.P.); and Clinical Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland (R.B.R.)
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Thomas E. Prisinzano
Department of Medicinal Chemistry, the University of Kansas, Lawrence, Kansas (C.W.C., T.E.P.); and Clinical Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland (R.B.R.)
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Eric L. Barker
Department of Medicinal Chemistry, the University of Kansas, Lawrence, Kansas (C.W.C., T.E.P.); and Clinical Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland (R.B.R.)
Roles: ASSOCIATE EDITOR
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Article Information

vol. 63 no. 2 316-347
DOI 
https://doi.org/10.1124/pr.110.003244
PubMed 
21444610

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online April 26, 2011.

Article Versions

  • Earlier version (March 28, 2011 - 05:41).
  • You are viewing the most recent version of this article.
Copyright & Usage 
U.S. Government work not protected by U.S. copyright

Author Information

  1. Christopher W. Cunningham,
  2. Richard B. Rothman, and
  3. Thomas E. Prisinzano
  1. Department of Medicinal Chemistry, the University of Kansas, Lawrence, Kansas (C.W.C., T.E.P.); and Clinical Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland (R.B.R.)
  1. Eric L. Barker, ASSOCIATE EDITOR
  1. Address correspondence to:
    Dr. Thomas E. Prisinzano, 1251 Wescoe Hall Drive, 4070 Malott Hall, Lawrence, KS 66045-7582. E-mail: prisinza{at}ku.edu
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Pharmacological Reviews: 63 (2)
Pharmacological Reviews
Vol. 63, Issue 2
1 Jun 2011
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Review ArticleReview Article

Neuropharmacology of the Naturally Occurring κ-Opioid Hallucinogen Salvinorin A

Christopher W. Cunningham, Richard B. Rothman and Thomas E. Prisinzano
Pharmacological Reviews June 1, 2011, 63 (2) 316-347; DOI: https://doi.org/10.1124/pr.110.003244

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Review ArticleReview Article

Neuropharmacology of the Naturally Occurring κ-Opioid Hallucinogen Salvinorin A

Christopher W. Cunningham, Richard B. Rothman and Thomas E. Prisinzano
Pharmacological Reviews June 1, 2011, 63 (2) 316-347; DOI: https://doi.org/10.1124/pr.110.003244
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  • Article
    • Abstract
    • I. Introduction
    • II. Ethnopharmacology and Constituents of S. divinorum
    • III. Metabolism and Pharmacokinetics of Salvinorin A
    • IV. Effects of Salvinorin A In Vitro
    • V. Effects of Salvinorin A In Vivo
    • VI. Summary and Future Directions
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • References
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