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Review ArticleReview Article

Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

Udai Bhan Pandey and Charles D. Nichols
Eric L. Barker, ASSOCIATE EDITOR
Pharmacological Reviews June 2011, 63 (2) 411-436; DOI: https://doi.org/10.1124/pr.110.003293
Udai Bhan Pandey
Departments of Genetics (U.B.P.) and Pharmacology and Experimental Therapeutics (C.D.N.), Louisiana State University Health Sciences Center, New Orleans, Louisiana
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Charles D. Nichols
Departments of Genetics (U.B.P.) and Pharmacology and Experimental Therapeutics (C.D.N.), Louisiana State University Health Sciences Center, New Orleans, Louisiana
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Eric L. Barker
Departments of Genetics (U.B.P.) and Pharmacology and Experimental Therapeutics (C.D.N.), Louisiana State University Health Sciences Center, New Orleans, Louisiana
Roles: ASSOCIATE EDITOR
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Article Information

vol. 63 no. 2 411-436
DOI 
https://doi.org/10.1124/pr.110.003293
PubMed 
21415126

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online April 26, 2011.

Article Versions

  • Earlier version (March 17, 2011 - 06:13).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Udai Bhan Pandey and
  2. Charles D. Nichols
  1. Departments of Genetics (U.B.P.) and Pharmacology and Experimental Therapeutics (C.D.N.), Louisiana State University Health Sciences Center, New Orleans, Louisiana
  1. Eric L. Barker, ASSOCIATE EDITOR
  1. Address correspondence to:
    Dr. Charles D. Nichols, Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, 1901 Perdido St., New Orleans, LA 70112. E-mail: cnich1{at}lsuhsc.edu.
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Funding

  • National Institutes of Health

    R01-MH083689

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Pharmacological Reviews: 63 (2)
Pharmacological Reviews
Vol. 63, Issue 2
1 Jun 2011
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Review ArticleReview Article

Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

Udai Bhan Pandey and Charles D. Nichols
Pharmacological Reviews June 1, 2011, 63 (2) 411-436; DOI: https://doi.org/10.1124/pr.110.003293

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Review ArticleReview Article

Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery

Udai Bhan Pandey and Charles D. Nichols
Pharmacological Reviews June 1, 2011, 63 (2) 411-436; DOI: https://doi.org/10.1124/pr.110.003293
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  • Article
    • Abstract
    • I. Introduction: Drug Discovery
    • II. D. melanogaster As a Model Organism
    • III. Considerations
    • IV. Therapeutic Areas and Opportunities to Use D. melanogaster in Drug Discovery
    • V. Successful Examples of D. melanogaster in the Drug Discovery Process
    • VI. Resources
    • Acknowledgments
    • Authorship Contributions
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