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Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets

Adam J. Kimple, Dustin E. Bosch, Patrick M. Giguère and David P. Siderovski
Arthur Christopoulos, ASSOCIATE EDITOR, Department of Pharmacology, UNC Neuroscience Center, and Lineberger Comprehensive Cancer Center, the University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina
Pharmacological Reviews September 2011, 63 (3) 728-749; DOI: https://doi.org/10.1124/pr.110.003038

Article Information

vol. 63 no. 3 728-749
DOI 
https://doi.org/10.1124/pr.110.003038
PubMed 
21737532
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0031-6997
Online ISSN 
1521-0081
History 
  • Published online July 19, 2011.

Article Versions

Copyright & Usage 
© 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Adam J. Kimple,
  2. Dustin E. Bosch,
  3. Patrick M. Giguère, and
  4. David P. Siderovski
  1. Department of Pharmacology, UNC Neuroscience Center, and Lineberger Comprehensive Cancer Center, the University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina
  1. Arthur Christopoulos, ASSOCIATE EDITOR
  1. Address correspondence to:
    Dr. David P. Siderovski, Department of Pharmacology, UNC School of Medicine, University of North Carolina at Chapel Hill, 4073 Genetic Medicine Bldg., CB#7365, 120 Mason Farm Road, Suite 4010, Chapel Hill, NC 27599-7365. E-mail: dsiderov{at}med.unc.edu
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Funding

  • National Institutes of Health

    R03-DA030555; R01-GM062338; R01-GM074268; R01-GM082892; T32-GM008719; T32-GM007040; F30-MH074266

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Review ArticleReview Article

Regulators of G-Protein Signaling and Their Gα Substrates: Promises and Challenges in Their Use as Drug Discovery Targets

Adam J. Kimple, Dustin E. Bosch, Patrick M. Giguère and David P. Siderovski
Pharmacological Reviews September 1, 2011, 63 (3) 728-749; DOI: https://doi.org/10.1124/pr.110.003038
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