Table of Contents

Review Articles

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  Organic Anion Transporters and Their Implications in Pharmacotherapy

  Arian Emami Riedmaier, Anne T. Nies, Elke Schaeffeler and Matthias Schwab

  Markku Koulu, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 421-449; DOI: https://doi.org/10.1124/pr.111.004614
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  Pharmacology and Therapeutics of Bronchodilators

  Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera

  David R. Sibley, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580
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  Physical and Chemical Strategies for Therapeutic Delivery by Using Polymeric Nanoparticles

  José M. Morachis, Enas A. Mahmoud and Adah Almutairi

  Paul A. Insel, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 505-519; DOI: https://doi.org/10.1124/pr.111.005363
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  Aldehyde Dehydrogenase Inhibitors: a Comprehensive Review of the Pharmacology, Mechanism of Action, Substrate Specificity, and Clinical Application

  Vindhya Koppaka, David C. Thompson, Ying Chen, Manuel Ellermann, Kyriacos C. Nicolaou, Risto O. Juvonen, Dennis Petersen, Richard A. Deitrich, Thomas D. Hurley and Vasilis Vasiliou

  David R. Sibley, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 520-539; DOI: https://doi.org/10.1124/pr.111.005538
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  Molecular Mechanisms Regulating the Vascular Prostacyclin Pathways and Their Adaptation during Pregnancy and in the Newborn

  Batoule H. Majed and Raouf A. Khalil

  Christopher J. Garland, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 540-582; DOI: https://doi.org/10.1124/pr.111.004770
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  The Pharmacological Treatment of Pulmonary Arterial Hypertension

  Lyn R. Frumkin

  Clive Page, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 583-620; DOI: https://doi.org/10.1124/pr.111.005587
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  Pharmacology for the Treatment of Premature Ejaculation

  François Giuliano and Pierre Clèment

  Ulf Simonsen, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 621-644; DOI: https://doi.org/10.1124/pr.111.004952
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  G-Protein-Coupled Receptors in Adult Neurogenesis

  Van A. Doze and Dianne M. Perez

  David R. Sibley, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 645-675; DOI: https://doi.org/10.1124/pr.111.004762
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  Classification, Functions, and Clinical Relevance of Extracellular Vesicles

  Edwin van der Pol, Anita N. Böing, Paul Harrison, Augueste Sturk and Rienk Nieuwland

  Mark P. Mattson, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 676-705; DOI: https://doi.org/10.1124/pr.112.005983
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  Cisplatin Resistance: A Cellular Self-Defense Mechanism Resulting from Multiple Epigenetic and Genetic Changes

  Ding-Wu Shen, Lynn M. Pouliot, Matthew D. Hall and Michael M. Gottesman

  David R. Sibley, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 706-721; DOI: https://doi.org/10.1124/pr.111.005637
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  Human Experimental Pain Models for Assessing the Therapeutic Efficacy of Analgesic Drugs

  Anne Estrup Olesen, Trine Andresen, Camilla Staahl and Asbjørn Mohr Drewes

  Ulf Simonsen, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 722-779; DOI: https://doi.org/10.1124/pr.111.005447
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  Thinking Outside the Cleft to Understand Synaptic Activity: Contribution of the Cystine-Glutamate Antiporter (System x_c⁻) to Normal and Pathological Glutamatergic Signaling

  Richard Bridges, Victoria Lutgen, Doug Lobner and David A. Baker

  Lynette C. Daws, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 780-802; DOI: https://doi.org/10.1124/pr.110.003889
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  The Dual Role of Pharmacogenetics in HIV Treatment: Mutations and Polymorphisms Regulating Antiretroviral Drug Resistance and Disposition

  Veronique Michaud, Tamara Bar-Magen, Jacques Turgeon, David Flockhart, Zeruesenay Desta and Mark A. Wainberg

  Theresa A. Shapiro, ASSOCIATE EDITOR

  Pharmacological Reviews July 2012, 64 (3) 803-833; DOI: https://doi.org/10.1124/pr.111.005553