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History
- Published online July 2, 2012.
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© 2012 by The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Anthony L. Gotter,
- Andrea L. Webber,
- Paul J. Coleman,
- John J. Renger, and
- Christopher J. Winrow
- Departments of Neuroscience (A.L.G., J.J.R., C.J.W.), Molecular Biomarkers (A.L.W.), and Medicinal Chemistry (P.J.C.), Merck Research Laboratories, West Point, Pennsylvania
- Address correspondence to:
Dr. Christopher J. Winrow, Merck & Co., Inc., 770 Sumneytown Pike, PO Box 4, West Point, PA 19486-0004. E-mail: christopher_winrow{at}merck.com
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- Article
- Abstract
- I. Introduction
- II. Discovery and Nomenclature of Orexin Signaling Components
- III. Orexin Receptor Reagents and Potential Therapeutics
- IV. Orexin Neurons Are a Key Component of Pathways Regulating Sleep
- V. Genetic and Pharmacological Dissection of Orexin-Mediated Arousal
- VI. Orexin Function beyond Sleep and Arousal
- VII. Conclusion
- Acknowledgments
- Authorship Contributions
- Footnotes
- References
- Figures & Data
- Info & Metrics
- eLetters
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