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Review ArticleReview Article

Pharmacology and Therapeutics of Bronchodilators

Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera
David R. Sibley, ASSOCIATE EDITOR
Pharmacological Reviews July 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580
Mario Cazzola
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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Clive P. Page
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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Luigino Calzetta
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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M. Gabriella Matera
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
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David R. Sibley
Department of Internal Medicine, Unit of Respiratory Clinical Pharmacology, University of Rome ‘Tor Vergata,’ Rome, Italy (M.C., L.C.); Department of Pulmonary Rehabilitation, San Raffaele Pisana Hospital, Istituto di Ricovero e Cura a Carattere Scientifico, Rome, Italy (M.C., L.C.); Sackler Institute of Pulmonary Pharmacology, Institute of Pharmaceutical Science, King's College London, London, UK (C.P.P., L.C.); and Department of Experimental Medicine, Unit of Pharmacology, Second University of Naples, Naples, Italy (M.G.M.)
Roles: ASSOCIATE EDITOR
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Pharmacological Reviews: 64 (3)
Pharmacological Reviews
Vol. 64, Issue 3
1 Jul 2012
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Review ArticleReview Article

PHARMACOLOGY AND THERAPEUTICS OF BRONCHODILATORS

Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera
Pharmacological Reviews July 1, 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580

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Review ArticleReview Article

PHARMACOLOGY AND THERAPEUTICS OF BRONCHODILATORS

Mario Cazzola, Clive P. Page, Luigino Calzetta and M. Gabriella Matera
Pharmacological Reviews July 1, 2012, 64 (3) 450-504; DOI: https://doi.org/10.1124/pr.111.004580
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  • Article
    • Abstract
    • I. Introduction: The Physiological Rationale for Using Bronchodilators
    • II. β-Adrenergic Receptor Agonists
    • III. Muscarinic Acetylcholine Receptor Antagonists
    • IV. Xanthines
    • V. Novel Classes of Bronchodilators
    • VI. Combination Therapy
    • VII. Controversies Surrounding Bronchodilators
    • VIII. The Role of Bronchodilators in the Management of Asthma and Chronic Obstructive Pulmonary Disease
    • IX. The Use of Bronchodilators in Special Populations
    • X. Pharmacogenetics of Airway Obstruction and the Future
    • Authorship Contributions
    • Footnotes
    • References
  • Figures & Data
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